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Evaluation of the stability and stratification of propofol and ketamine mixtures for pediatric anesthesia

Paediatric Anaesthesia · Mart 2018

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YÖKSİS Kayıtları
Evaluation of the stability and stratification of propofol and ketamine mixtures for pediatric anesthesia
Pediatric Anesthesia · 2018 SCI-Expanded
Doç. Dr. MEHMET SELÇUK ULUER →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 12 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Left femoral vein is a better choice for cannulation in children a computed tomography study
2013 ISSN: 11555645 SCI-Expanded
Prof. Dr. İLHAN ÇİFTCİ →
Efficacy of a low dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair
2009 ISSN: 11555645 SCI-Expanded
Prof. Dr. İLHAN ÇİFTCİ →
Left femoral vein is a better choice for cannulation in children a computed tomography study
2013 ISSN: 11555645 SCI-Expanded 1 atıf
Prof. Dr. İLHAN ÇİFTCİ →
Efficacy of a low dose spinal morphine with bupivacaine for postoperative analgesia in children undergoing hypospadias repair
2009 ISSN: 11555645 SSCI
Prof. Dr. İLHAN ÇİFTCİ →
Left femoral vein is a better choice for cannulation in children a computed tomography study
2013 ISSN: 11555645 SSCI
Prof. Dr. JALE BENGİ ÇELİK →
Left femoral vein is a better choice for cannulation in children a computed tomography study
2013 ISSN: 11555645 SCI-Expanded
Prof. Dr. BAHATTİN KEREM AYDIN →
Unilateral spinal anesthesia in a pediatric patient with Duchenne muscular dystrophy a case report
2013 ISSN: 11555645 SCI-Expanded
Prof. Dr. İNCİ KARA →
Unilateral spinal anesthesia in a pediatric patient with Duchenne muscular dystrophy a case report
2013 ISSN: 11555645 SCI
Prof. Dr. BAHAR ÖÇ →
Left femoral vein is a better choice for cannulation in children: a computed tomography study
2013 ISSN: 11555645 SCI-Expanded
Prof. Dr. İLHAN ÇİFTCİ →
The effects of bispectral index monitoring on hemodynamics and recovery profile in developmentally delayed pediatric patients undergoing dental surgery
2015 ISSN: 11555645 SCI-Expanded
Prof. Dr. MEHMET SARGIN →
The effects of bispectral index monitoring on hemodynamics and recovery profile in developmentally delayed pediatric patients undergoing dental surgery
2015 ISSN: 11555645 SCI-Expanded
Doç. Dr. MEHMET SELÇUK ULUER →
Evaluation of the stability and stratification of propofol and ketamine mixtures for pediatric anesthesia
2018 ISSN: 11555645 SCI-Expanded
Doç. Dr. MEHMET SELÇUK ULUER →

Makale Bilgileri

Dergi Paediatric Anaesthesia
ISSN11555645
Yayın TarihiMart 2018
Cilt / Sayfa28 · 275-280
DOI10.1111/pan.13318
Scopus ID2-s2.0-85041952282
Özet Background: The combination of propofol and ketamine is commonly used for total intravenous anesthesia. These drugs can be delivered in different syringes or in the same syringe. We hypothesized that the drugs might separate and different concentrations of each drug could be found in different parts of the syringe during the procedure period when they were mixed in 1 syringe. Methods: Twelve 60-mL polypropylene syringes were prepared by mixing propofol and ketamine as 4 groups on the basis of propofol/ketamine mixture ratios (5:1 and 6.7:1) and propofol solution concentrations. Syringes were placed upright in the vertical position into a rack and kept at room temperature (21.5-22.5°C), in daylight conditions and were not moved for 360 minutes. Samples of the mixture were taken from both the top and the bottom of the syringe. The first 1 mL of the samples was discarded, the following second 1 mL of the samples was filtered using 0.2-μm polytetrafluoroethylene filters and measured twice (n = 6). Samples were taken at the following time intervals: T0, T10, T30, T60, T90, T120, T180, T240, T300, and T360 min. Syringes were checked visually for any color change and separation lines between the drugs. Results: There were no significant differences between the propofol and ketamine concentrations of the top and bottom samples in all 4 groups. In addition, there were no statistically significant changes of propofol and ketamine concentrations of samples over 360 minutes in any of the 4 groups. No visual changes were observed during 6 hours’ observation. Conclusion: The results of our measurements demonstrated that mixtures of propofol (1% and 2%) and ketamine at 5:1 and 6.7:1 ratios could be used in terms of mixture homogeneity and stability in a polypropylene syringe during a 6-hour period at room temperature.

Yazarlar (6)

1
Murat Izgi
ORCID: 0000-0003-2747-7290
2
Betül Başaran
3
Ahmet Muderrisoglu
4
Aysun Ankay Yilbas
5
Mehmet Selçuk Uluer
6
Bilge Celebioglu

Anahtar Kelimeler

general anesthesia intravenous agents total intravenous anesthesia

Kurumlar

Hacettepe Üniversitesi
Ankara Turkey
Konya Meram Training and Research Hospital
Konya Turkey
Scimago Dergi (ISSN Eşleşmesi)
Paediatric Anaesthesia
Q2
SJR Skoru0,658
H-Index102
YayıncıJohn Wiley and Sons Inc
ÜlkeUnited Kingdom
Anesthesiology and Pain Medicine (Q2)
Pediatrics, Perinatology and Child Health (Q2)
Dergi sayfasına git

Metrikler

13
Atıf
6
Yazar
3
Anahtar Kelime

Sistemimizdeki Yazarlar

MU
MEHMET SELÇUK ULUER
Doç. Dr.

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