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Hyoscine N-Butylbromide for Preventing Propofol Injection Pain: A Randomized, Placebo-Controlled and Double-Blind Study

Medical Principles and Practice · Nisan 2018

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YÖKSİS Kayıtları
Hyoscine N-Butylbromide for Preventing Propofol Injection Pain: A Randomized, Placebo-Controlled and Double-Blind Study
Medical Principles and Practice · 2018 SCI-Expanded
DOÇENT MEHMET SELÇUK ULUER →
Hyoscine N-Butylbromide for Preventing Propofol Injection Pain: A Randomized, Placebo-Controlled and Double-Blind Study
Medical Principles and Practice · 2018 SCI-Expanded
PROFESÖR MEHMET SARGIN →

Makale Bilgileri

DergiMedical Principles and Practice
Yayın TarihiNisan 2018
Cilt / Sayfa27 · 39-43
DOI10.1159/000486747
Scopus ID2-s2.0-85045855866
Erişim🔓 Açık Erişim
Özet Objective: In this study, the aim was to investigate the effect of hyoscine N-butylbromide (HnBB) pretreatment on pain during propofol injection. Subjects and Methods: In this prospective, randomized, placebo-controlled and double-blind trial, 60 patients scheduled to undergo routine outpatient surgery under general anesthesia were randomly allocated to 2 groups, the HnBB (n = 30) and sodium chloride (n = 30) groups. Twenty seconds after the injection of 20 mg HnBB or 0.9 % sodium chloride, a 50-mg dose of propofol was injected in 2-3 s. Ten seconds later, the pain intensity was assessed using a 4-point scale: no pain (0), mild (1), moderate (2), and severe (3) pain. The Student t test was used for the analysis of parametric data and the Pearson χ2 test for categorical data. Results: The occurrence of pain in the HnBB group (43.3%) was significantly lower than the control group (73.3%) (p < 0.018). Of the 30 patients in each group, 10 in the control group and 3 in the HnBB group experienced severe pain (p = 0.001). Conclusions: Pretreatment with 20 mg HnBB significantly reduced propofol injection pain compared to placebo.

Yazarlar (3)

1
Mehmet Sargln
2
Mehmet Selçuk Uluer
3
Eyüp Aydoǧan

Anahtar Kelimeler

Hyoscine N-butylbromide Injection pain Propofol

Kurumlar

Konya Meram Training and Research Hospital
Konya Turkey

Metrikler

5
Atıf
3
Yazar
3
Anahtar Kelime

Sistemimizdeki Yazarlar

MU
MEHMET SELÇUK ULUER
DOÇENT

Hızlı Erişim

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