Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
Food and Chemical Toxicology · Şubat 2018
YÖKSİS Kayıtları
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
FOOD AND CHEMICAL TOXICOLOGY · 2018 SCI
Prof. Dr. AHMET UYSAL →
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
FOOD AND CHEMICAL TOXICOLOGY · 2018 SCI
Prof. Dr. GÖKHAN ZENGİN →
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
FOOD AND CHEMICAL TOXICOLOGY · 2018 SCI
Dr. Öğr. Üyesi ERDOĞAN GÜNEŞ →
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
FOOD AND CHEMICAL TOXICOLOGY · 2018 SCI
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey
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Screening for in vitro antioxidant properties and fatty acid profiles of five Centaurea L species from Turkey flora
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Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L species
2013 ISSN: 02786915 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L species
2013 ISSN: 02786915 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening for in vitro antioxidant properties and fatty acid profiles of five Centaurea L species from Turkey flora
2011 ISSN: 02786915 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey
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Organochlorine pesticide residues in wheat from Konya region Turkey
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Mineral and heavy metal levels of some fruits grown at the roadsides
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Mineral and heavy metal levels of some fruits grown at the roadsides
2010 ISSN: 0278-6915 SSCI 23 atıf
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Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L dill samples cultivated under organic and conventional agricultural conditions
2013 ISSN: 0278-6915 SCI-Expanded Q1
Dr. Öğr. Üyesi SADİYE AYŞE ÇELİK →
Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents
2018 ISSN: 0278-6915 SCI
Dr. Öğr. Üyesi ERDOĞAN GÜNEŞ →
Novel in vitro and in silico insights of the multi-biological activities and chemical composition of Bidens tripartita L.
2018 ISSN: 02786915 SCI
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Bioactivities of Achillea phrygia and Bupleurum croceum based on the composition of phenolic compounds: In vitro and in silico approaches
2017 ISSN: 02786915 SCI
Prof. Dr. GÖKHAN ZENGİN →
Bioactivities of Achillea phrygia and Bupleurum croceum based on the composition of phenolic compounds: In vitro and in silico approaches
2017 ISSN: 02786915 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Combining in vitro , in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea
2017 ISSN: 02786915 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Evaluation of antioxidant potential, enzyme inhibition activity and phenolic profile of Lathyrus cicera and Lathyrus digitatus : Potential sources of bioactive compounds for the food industry
2017 ISSN: 02786915 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Combining in vitro , in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea
2017 ISSN: 02786915 SCI
Prof. Dr. GÖKHAN ZENGİN →
UHPLC-QTOF-MS analysis of bioactive constituents from two Romanian Goji (Lycium barbarum L.) berries cultivars and their antioxidant, enzyme inhibitory, and real-time cytotoxicological evaluation
2018 ISSN: 0278-6915 SCI
Prof. Dr. GÖKHAN ZENGİN →
Investigations into the therapeutic potential of Asphodeline liburnica roots: In vitro and in silico biochemical and toxicological perspectives
2018 ISSN: 0278-6915 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Novel in vitro and in silico insights of the multi-biological activities and chemical composition of Bidens tripartita L.
2018 ISSN: 0278-6915 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Makale Bilgileri
ISSN02786915
Yayın TarihiŞubat 2018
Cilt / Sayfa112 · 448-457
Scopus ID2-s2.0-85027728850
Özet
This study gathers information about the effects of different extracts (methanol and water) from rhizomes and aerial parts of Iris schachtii on selected enzymes (cholinesterases, alpha-amylase and alpha-glucosidase, tyrosinase and lipase) as well as of their antioxidant capacities and antimutagenic properties in relation with their phenolic composition. The chemical composition was assessed by determining total phenolic and flavonoid content as well as individual phenolic compounds by HPLC-DAD. Moreover, antioxidant abilities of the investigated extracts were tested by using different assays including free radical scavenging (DPPH and ABTS), reducing power (CUPRAC and FRAP), phosphomolybdenum and metal chelating, overall rhizomes being indicated as a superior source of antioxidant compounds. HPLC analysis revealed the abundance of some phenolics including apigenin (2584 μg/g extract) and luteolin (2510 μg/g extract) in aerial parts extracts while rhizomes were rich in apigenin (4734 μg/g extract) and kaempferol (4214 μg/g extract). The methanolic extracts exhibited a high anti-lipase activity while all extracts presented a relatively high inhibition on α-glucosidase. Furthermore, interactions between dominant compounds from extracts and selected enzymes were investigated by molecular modeling studies in order to explain at a molecular level the interactions between selected compounds and active sites of the enzyme/s.
Yazarlar (7)
1
Andrei Mocan
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Adriano Mollica
4
Ahmet Uysal
5
Erdogan Gunes
6
Gianina Crişan
7
Abdurrahman Aktumsek
Anahtar Kelimeler
Bioactive compounds
Enzyme inhibition
Herbal extracts
Iris schachtii
Ornamental crops
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
Universitatea de Stiinte Agricole si Medicina Veterinara din Cluj-Napoca
Cluj Napoca Romania
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Scimago Dergi (ISSN Eşleşmesi)
Food and Chemical Toxicology
Q1
SJR Skoru0,750
H-Index223
YayıncıElsevier Ltd
ÜlkeUnited Kingdom
Food Science (Q1)
Medicine (miscellaneous) (Q2)
Toxicology (Q2)
Metrikler
42
Atıf
7
Yazar
5
Anahtar Kelime