Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Assessment of serum neopterin and calprotectin as biomarkers for subclinical inflammation in patients with familial Mediterranean fever
Irish Journal of Medical Science · Ağustos 2023
YÖKSİS Kayıtları
Assessment of serum neopterin and calprotectin as biomarkers for subclinical inflammation in patients with familial Mediterranean fever
Springer Science and Business Media LLC · 2022 SCI-Expanded
PROFESÖR ABDULLAH SİVRİKAYA →
Assessment of serum neopterin and calprotectin as biomarkers for subclinical inflammation in patients with familial Mediterranean fever
, Irish Journal of Medical Science · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MUSLU KAZIM KÖREZ →
Assesment of Serum Neopterin and Calprotectin as Biomarkers for Subclinical Inflammation in Patients with Familial Mediterranean Fever
Irish Journal of Medical Science · 2023 SCI-Expanded
PROFESÖR SEMA YILMAZ →
Makale Bilgileri
DergiIrish Journal of Medical Science
Yayın TarihiAğustos 2023
Cilt / Sayfa192 · 2015-2022
Scopus ID2-s2.0-85138801507
Erişim🔓 Açık Erişim
Özet
Background: Familial Mediterranean fever (FMF) is the most common autoinflammatory disease characterized by short, repeated, and self-limiting attacks of fever and serositis. Subclinical inflammation can persist in the periods with no symptoms and result in amyloidosis even with colchicine treatment. Neopterin and calprotectin have been considered essential players in inflammation and immune response. Aim: The study was aimed to measure serum levels of neopterin and calprotectin in patients with FMF in the attack-free period. Methods: A total of 160 participants were recruited from the rheumatology department in this single-center, case–control study. Individuals having the inclusion criteria were divided into healthy controls (n = 80) and FMF (n = 80). The laboratory data were acquired from the electronic registration database. Serum calprotectin and neopterin were measured with ELISA test kits. FMF patients and healthy controls’ laboratory findings were compared. Results: FMF patients’ serum red cell distribution width (RDW), calprotectin, and neopterin values were significantly higher compared to healthy controls. There were no statistically significant differences between calprotectin and neopterin regarding gender, family history, and colchicine response of the FMF patients. Conclusions: Calprotectin, neopterin, and RDW can be valuable marker candidates to be used in the follow-up of subclinical inflammation in FMF patients.
Yazarlar (7)
1
Dilek Tezcan
ORCID: 0000-0002-8295-9770
2
Duygu Eryavuz Onmaz
ORCID: 0000-0001-8564-1824
3
Abdullah Sivrikaya
4
Selda Hakbilen
ORCID: 0000-0002-6417-7310
5
M. K. Korez
ORCID: 0000-0001-9524-6115
6
Semral Gülcemal
ORCID: 0000-0002-6085-9939
7
Sema Yılmaz
ORCID: 0000-0003-4277-3880
Anahtar Kelimeler
Calprotectin
Familial Mediterranean fever
Inflammation
Neopterin
Red cell distribution width
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
University of Health Sciences
Istanbul Turkey
Metrikler
3
Atıf
7
Yazar
5
Anahtar Kelime