Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
The effectiveness of anti- R. equi hyperimmune plasma against R. equi challenge in thoroughbred Arabian foals of mares vaccinated with R. equi vaccine
Scientific World Journal · Ocak 2014
YÖKSİS Kayıtları
The Effectiveness of Anti R equi Hyperimmune Plasma against R equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded 2 atıf
Prof. Dr. ÖZGÜR ÖZDEMİR →
The Effectiveness of Anti R equi Hyperimmune Plasma against R equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded 1 atıf
Prof. Dr. MEHMET MADEN →
The Effectiveness of Anti R equi Hyperimmune Plasma against R equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded 1 atıf
Prof. Dr. ZAFER SAYIN →
The Effectiveness of Anti R equi Hyperimmune Plasma against R equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded 1 atıf
Doç. Dr. ASLI BALEVİ →
The Effectiveness of Anti-R. equi Hyperimmune Plasma against R. equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R-equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded
Prof. Dr. OSMAN ERGANİŞ →
The Effectiveness of Anti-R. equi Hyperimmune Plasma against R. equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R-equi Vaccine
The Scientific World Journal · 2014 SCI-Expanded
Prof. Dr. MEHMET MADEN →
The Effectiveness of Anti-R. equi Hyperimmune Plasma againstR. equi Challenge in Thoroughbred Arabian Foals of Mares Vaccinated with R. equi Vaccine
The Scientific World Journal · 2014 SCI
Dr. Öğr. Üyesi YASEMİN KARYEYEN →
Makale Bilgileri
Dergi
Scientific World Journal
Yayın TarihiOcak 2014
Cilt / Sayfa2014
Scopus ID2-s2.0-84899418755
Erişim🔓 Açık Erişim
Özet
This study aimed to determine the effectiveness of a pregnant mare immunization of a Rhodococcus equi (R. equi) vaccine candidate containing a water-based nanoparticle mineral oil adjuvanted (Montanide IMS 3012) inactive bacterin and virulence-associated protein A (VapA), as well as the administration of anti-R. equi hyperimmune (HI) plasma against R. equi challenge in the mares' foals. The efficacy of passive immunizations (colostral passive immunity by mare vaccination and artificial passive immunity by HI plasma administration) was evaluated based on clinical signs, complete blood count, blood gas analysis, serological response (ELISA), interleukin-4 (IL-4) and interferon gamma (IFN-γ), total cell count of the bronchoalveolar lavage fluids (BALF) samples, reisolation rate of R. equi from BALF samples (CFU/mL), lung samples (CFU/gr), and lesion scores of the organs and tissue according to pathological findings after necropsy in the foals. The vaccination of pregnant mares and HI plasma administration in the foals reduced the severity of R. equi pneumonia and lesion scores of the organs and tissue by 3.54-fold compared to the control foals. This study thus indicates that immunization of pregnant mares with R. equi vaccine candidate and administration of HI plasma in mares' foals effectively protect foals against R. equi challenge. © 2014 Osman Erganis et al.
Yazarlar (7)
1
O. Erganiş
2
Zafer Sayın
3
H. H. Hadimli
4
Aslı Sakmanoğlu
5
Yasemin Pinarkara
6
O. Ozdemir
7
Mehmet Maden
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
17
Atıf
7
Yazar