Scopus
YÖKSİS Eşleşti
Coenzyme Q10 and its relation with oxidant and antioxidant system markers in patients with end-stage renal disease
Renal Failure · Ağustos 2011
YÖKSİS Kayıtları
Coenzyme Q 10 and its Relation with Oxidant and Antioxidant SystemMarkers in Patients with End Stage Renal Disease
RENAL FAILURE · 2011 SSCI 3 atıf
PROFESÖR NİLSEL OKUDAN →
Coenzyme Q10 and its Relation with Oxidant and Antioxidant System Markers in Patients with End Stage Renal Disease
Renal Failure · 2011 SCI-Expanded
PROFESÖR MUAZ BELVİRANLI →
Makale Bilgileri
DergiRenal Failure
Yayın TarihiAğustos 2011
Cilt / Sayfa33 · 677-681
Scopus ID2-s2.0-79960823224
Özet
Rationale and objectives: Oxidative stress is increased in chronic kidney disease (CKD) patients and end-stage renal disease (ESRD) patients undergoing dialysis treatment. Coenzyme Q10 (CoQ10) is a ubiquitous and strong antioxidant. Role of CoQ10 is not fully evaluated in renal patients. We aimed to investigate the relationship of CoQ10 with oxidant and antioxidant system markers in patients with renal disease. Material and methods: Forty patients with CKD (stages 35) who were managed conservatively without dialysis treatment, 40 hemodialysis, and 60 chronic ambulatory peritoneal dialysis (CAPD) patients were included in the study. Biochemical and whole blood analyses were done using hospital auto-analyzers from stored samples. Serum CoQ10, malondialdehyde (MDA), superoxide dismutase (SOD), and antioxidant activity (AOA) levels were determined. Main findings: There was no difference among the groups in terms of serum CoQ10 levels. However, other components of antioxidant system, namely, SOD and AOA were significantly higher in CAPD patients when compared to CKD patients. MDA levels were not significantly different among the groups. Principal conclusion(s): The results of this study showed no difference among CKD, CAPD, and hemodialysis patients in terms of serum CoQ10 levels. © 2011 Informa Healthcare USA, Inc.
Yazarlar (6)
1
H. Gökbel
2
Huseyin Atalay
3
Nilsel Okudan
4
Yalcin Solak
5
Muaz Belviranli
6
Suleyman Turk
Anahtar Kelimeler
Antioxidant system
Chronic kidney disease
Coenzyme Q10
Hemodialysis
Malondialdehyde
Oxidative stress
Peritoneal dialysis
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
12
Atıf
6
Yazar
7
Anahtar Kelime