Scopus
YÖKSİS Eşleşti
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
Nanomedicine · Ekim 2023
YÖKSİS Kayıtları
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
Nanomedicine · 2023 SCI
PROFESÖR SERDAR KARAKURT →
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
Nanomedicine · 2023 SCI-Expanded
PROFESÖR GÜLŞİN ARSLAN →
Investigation of in vitro antimicrobial and
cytotoxic effects of gold nanoparticles
capped with meropenem and imipenem
Nanomedicine · 2023 SCI-Expanded
PROFESÖR UĞUR ARSLAN →
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
Nanomedicine · 2023 SCI-Expanded
PROFESÖR İDRİS SARGIN →
Makale Bilgileri
DergiNanomedicine
Yayın TarihiEkim 2023
Cilt / Sayfa18 · 1719-1731
Scopus ID2-s2.0-85178497723
Özet
Aim: This study aimed to investigate the in vitro antimicrobial effect of gold nanoparticles capped with meropenem and imipenem against various strains and to evaluate the cytotoxic effect of gold nanoparticles on healthy human colon epithelial cells. Materials & methods: Gold nanoparticles were synthesized via the Turkevich method and tested for antimicrobial effects using broth microdilution. Cell culture studies were performed using a cytotoxicity assay with alamarBlue™. Results & conclusion: Nanoparticles (10–20 nm) with antibiotic coating were more effective against Escherichia coli, Proteus spp. and Serratia marcescens than pure antibiotics. They had a cytotoxic effect on cells at high concentrations but were safe at low concentrations.
Yazarlar (5)
1
Nurullah Ciftci
2
Idris Sargin
ORCID: 0000-0003-3785-9575
3
Gulsin Arslan
4
Serdar Karakurt
5
Ugur Arslan
Anahtar Kelimeler
antimicrobial resistance
cell culture
gold nanoparticles
imipenem
meropenem
Kurumlar
Kafkas Üniversitesi
Kars Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
5
Yazar
5
Anahtar Kelime