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Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co-administration in healthy and endotoxaemic rabbits

Veterinary Journal · Eylül 2008

YÖKSİS DOI Eşleşmesi Bulundu

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YÖKSİS Kayıtları
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co administration in healthy and endotoxaemic rabbits
The Veterinary Journal · 2008 SCI-Expanded 12 atıf
Prof. Dr. KAMİL ÜNEY →
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co administration in healthy and endotoxaemic rabbits
The Veterinary Journal · 2008 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co-administration in healthy and endotoxaemic rabbits
The Veterinary Journal · 2008 SCI-Expanded
Prof. Dr. ENVER YAZAR →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 9 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co administration in healthy and endotoxaemic rabbits
2008 ISSN: 10900233 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
Effect of Experimental Therapeutic Ultrasound on the Distal Antebrachial Growth Plates in One Month Old Rabbits
2002 ISSN: 10900233 SSCI
Prof. Dr. İLHAMİ ÇELİK →
Effect Of Experimental Therapaeutic Ultrasound On The Distal Antebrachial Growth Plates In One Month Old Rabbits
2002 ISSN: 1090-0233 SCI
Prof. Dr. MURAT BOYDAK →
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co-administration in healthy and endotoxaemic rabbits
2008 ISSN: 10900233 SCI-Expanded
Prof. Dr. ENVER YAZAR →
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co administration in healthy and endotoxaemic rabbits
2008 ISSN: 10900233 SCI-Expanded 12 atıf
Prof. Dr. KAMİL ÜNEY →
Effect of experimental therapeutic ultrasound on the distal antebrachial growth plates in one-month-old rabbits
2002 ISSN: 1090-0233 SCI-Expanded
Prof. Dr. FAHRETTİN ALKAN →
Liraglutide as a novel therapeutic for overweight in canines: A clinical study
2025 ISSN: 1090-0233 SSCI Q1
Arş. Gör. ZEKERİYA SAFA İNANÇ →
Liraglutide as a novel therapeutic for overweight in canines: A clinical study
2025 ISSN: 1090-0233 SCI-Expanded Q1
Doç. Dr. DURMUŞ HATİPOĞLU →
Liraglutide as a novel therapeutic for overweight in canines: A clinical study
2025 ISSN: 1090-0233 SCI-Expanded Q1
Prof. Dr. BURAK DİK →

Makale Bilgileri

Dergi Veterinary Journal
ISSN10900233
Yayın TarihiEylül 2008
Cilt / Sayfa177 · 418-424
DOI10.1016/j.tvjl.2007.05.021
Scopus ID2-s2.0-46049087185
Özet The purpose of this study was to determine the pharmacokinetics and possible interactions of enrofloxacin (ENR) and flunixin meglumine (FM) in healthy rabbits and in rabbits where endotoxaemia had been induced by administering Escherichia coli lipopolysaccharide (LPS). Six male adult New Zealand White rabbits were used for the study. In Phase I, FM (2.2 mg/kg) and ENR (5 mg/kg) were given simultaneously as a bolus intravenous (IV) injection to each healthy rabbit. After a washout period, Phase II consisted of purified LPS administered as an IV bolus injection, then FM and ENR. LPS produced statistically significant increases in some serum biochemical concentrations. After the drugs were co-administered, the kinetic parameters of FM were not significantly different in healthy compared to endotoxaemic rabbits. It is concluded that ENR and FM could be co-administered to rabbits to treat endotoxaemia as no negative interaction was observed between the pharmacokinetics of both drugs. © 2007 Elsevier Ltd. All rights reserved.

Yazarlar (5)

1
M. Elmas
2
E. Yazar
3
Kamil Üney
ORCID: 0000-0002-8674-4873
4
Ayşe Er (Karabacak)
5
B. Traş

Anahtar Kelimeler

Endotoxaemia Enrofloxacin Flunixin meglumine Pharmacokinetics Rabbits

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Veterinary Journal
Q1
SJR Skoru0,739
H-Index139
YayıncıBailliere Tindall Ltd
ÜlkeUnited Kingdom
Animal Science and Zoology (Q1)
Veterinary (miscellaneous) (Q1)
Dergi sayfasına git

Metrikler

25
Atıf
5
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

KÜ
KAMİL ÜNEY
Prof. Dr.

Hızlı Erişim

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