Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
Polish Journal of Veterinary Sciences · Ocak 2023
YÖKSİS Kayıtları
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
Polish Journal of Veterinary Sciences · 2023 SCI-Expanded
Doç. Dr. MERVE İDER →
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
Polish journal of veterinary sciences · 2023 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
Polish Journal of Veterinary Sciences · 2023 SCI-Expanded
Prof. Dr. MAHMUT OK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. AMİR NASERİ →
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI
Prof. Dr. HASAN GÜZELBEKTEŞ →
The level of serum ionised calcium, aspartate aminotransferase, insulin, glucose, betahydroxybutyrate concentrations and blood gas parameters in cows with left displacement of abomasum
2006 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MAHMUT OK →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MUSTAFA ARICAN →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. RAMAZAN ÇÖL →
Glucose-6-phosphate dehydrogenase,glutathione peroxidase, total glutationeand reduced nicotinamide adeninedinucleotide phosphate in milk cellsof subclinical mastitic cows
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MAHMUT OK →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MEHMET MADEN →
The clinical efficacy of pentoxifylline
and l-glutamine on ischemia and reperfusion
injury in cattle with displaced abomasum:
a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. KURTULUŞ PARLAK →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MUSTAFA ARICAN →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q2
Prof. Dr. BÜNYAMİN TRAŞ →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. RAMAZAN ÇÖL →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. KAMİL ÜNEY →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. BURAK DİK →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. ZAFER SAYIN →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. OSMAN ERGANİŞ →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 15051773 SCI Q3
Prof. Dr. BÜNYAMİN TRAŞ →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. ALİ USLU →
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
2023 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
Makale Bilgileri
ISSN15051773
Yayın TarihiOcak 2023
Cilt / Sayfa26 · 5-12
Scopus ID2-s2.0-85151044739
Erişim🔓 Açık Erişim
Özet
The aim of this study was to investigate the cardiotoxic effect of the combination of tilmicosin and diclofenac sodium in sheep. Thirty-two sheep were used and were randomly divided into four equal groups as tilmicosin (T), diclofenac sodium (D), tilmicosin+diclofenac sodium (TD) and control (C) group. Group T received a single dose of tilmicosin, Group D was administered diclofenac sodium once a day for 3 days, and group TD was administered diclofenac and tilmicosin at the same doses as group T and D. Group C received NaCl in a similar way. The blood samples were taken before dosing and at 4th, 8th, 24th and 72nd hour post-dosing for measurement of cardiac markers such as H-FABP, cTn-I, CK-MB. H-FABP level of group TD was found to be significantly (p<0.05) higher than of group C at the 8th, 24th and 72nd hour and group D and T at the 72nd hour. cTn-I and CK-MB levels of group TD were found significantly (p<0.05) higher compared with other groups. In conclusion, the combined use of tilmicosin and diclofenac in sheep causes an increase in cardiac biomarkers and it can be stated that this combination of drugs may cause cardiac damage.
Yazarlar (7)
1
Ramazan Yildiz
2
D. Durna Corum
3
Orhan Corum
ORCID: 0000-0003-3168-2510
4
Merve Ider
ORCID: 0000-0003-2928-5452
5
O. Atik
6
M. Ok
7
Kamil Üney
ORCID: 0000-0002-8674-4873
Anahtar Kelimeler
cardiotoxicity
diclofenac
H-FABP
sheep
tilmicosin
Kurumlar
Afyon Kocatepe Üniversitesi
Afyonkarahisar Turkey
Mehmet Akif University
Burdur Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Hatay Mustafa Kemal
Hatay Turkey
Scimago Dergi (ISSN Eşleşmesi)
Polish Journal of Veterinary Sciences
Q2
SJR Skoru0,348
H-Index39
YayıncıPolska Akademia Nauk
ÜlkePoland
Veterinary (miscellaneous) (Q2)
Medicine (miscellaneous) (Q3)
Metrikler
3
Atıf
7
Yazar
5
Anahtar Kelime