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Scopus YÖKSİS DOI Eşleşti SJR Q2

Pharmacokinetics of oxfendazole and oxyclozanide following single and combined oral administration in goats

Small Ruminant Research · Şubat 2023

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YÖKSİS Kayıtları
Pharmacokinetics of oxfendazole and oxyclozanide following single and combined oral administration in goats
Small Ruminant Research · 2023 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Pharmacokinetics of oxfendazole and oxyclozanide following single and combined oral administration in goats
SMALL RUMINANT RESEARCH · 2023 SCI-Expanded
Prof. Dr. BÜNYAMİN TRAŞ →
Pharmacokinetics of oxfendazole and oxyclozanide following single and combined oral administration in goats
SMALL RUMINANT RESEARCH · 2023 SCI-Expanded
Prof. Dr. BÜNYAMİN TRAŞ →
Pharmacokinetics of oxfendazole and oxyclozanide following single and combined oral administration in goats
SMALL RUMINANT RESEARCH · 2023 SCI-Expanded
Prof. Dr. BÜNYAMİN TRAŞ →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
The effects of different silage additives on rumen protozoan number and volatile fatty acid concentration in sheep fed corn silage
2003 ISSN: 09214488 SCI-Expanded 31 atıf
Prof. Dr. NURCAN DÖNMEZ →
Relationship of blood and seminal plasma ceruloplasmin copper iron and cadmium concentrations with sperm quality in Merino rams
2015 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Effect of anti oxidants and oxidative stress parameters on ram semen after the freeze thawing process
2008 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Effects of anti oxidant additives on microscopic and oxidative parameters of Angora goat semen following the freeze thawing process
2008 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Protective effect of taurine glutathione and trehalose on the liquid storage of ram semen
2007 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Comparison of the effects of glutamine and an amino acid solution on post thawed ram sperm parameters lipid peroxidation and anti oxidant activities
2009 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
The effect of antioxidants on post thawed Angora goat Capra hircus ancryrensis sperm parameters lipid peroxidation and antioxidant activities
2010 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Ergothioneine attenuates the DNA damage of post thawed Merino ram sperm
2012 ISSN: 09214488 SCI-Expanded
Prof. Dr. MUSTAFA NUMAN BUCAK →
Ergothioneine attenuates the DNA damage of post thawed Merino ram sperm
2012 ISSN: 09214488 SCI-Expanded 1 atıf
Prof. Dr. NURİ BAŞPINAR →
Relationship of blood and seminal plasma ceruloplasmin copper iron and cadmium concentrations with sperm quality in merino rams
2015 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
The effect of 12 successive blood passages on the virulence of Babesia ovis in splenectomized lambs A preliminary study
2014 ISSN: 09214488 SCI-Expanded
Prof. Dr. NERMİN IŞIK USLU →
Lipolysis in Tulum cheese produced from raw and pasteurized goats milk during ripening
2014 ISSN: 09214488 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Attenuating the endotoxin induced acute phase response by pentoxifylline in comparison with dexamethasone and ketoprofen in sheep
2015 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. MEHMET MADEN →
Investigation of interferon tau stimulated genes ISGs simultaneously in the endometrium corpus luteum CL and peripheral blood leukocytes PBLs in the preluteolytic stage of early pregnancy in ewes
2016 ISSN: 09214488 SCI-Expanded Q2
Dr. Öğr. Üyesi GONCA SÖNMEZ →
Rapid diagnosis of ovine Brucella Campylobacter and Salmonella infections from fetal stomach contents by coagglutination test
2002 ISSN: 09214488 SSCI
Prof. Dr. OSMAN ERGANİŞ →
Influence of lycopene and cysteamine on sperm and oxidative stress parameters during liquid storage of ram semen at 5 degrees C
2016 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Pharmacokinetics of ceftriaxone following single ascending intravenous doses in sheep
2018 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. AYŞE ER →
Pharmacokinetics and bioavailability of marbofloxacin in lambs following administration of intravenous, intramuscular and subcutaneous
2018 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Pharmacokinetics of ceftriaxone following single ascending intravenous doses in sheep
2018 ISSN: 0921-4488 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Pharmacokinetics of marbofloxacin following intramuscular administration at different doses in sheep
2019 ISSN: 0921-4488 SCI
Prof. Dr. KAMİL ÜNEY →

Makale Bilgileri

Dergi Small Ruminant Research
ISSN09214488
Yayın TarihiŞubat 2023
Cilt / Sayfa219
DOI10.1016/j.smallrumres.2023.106916
Scopus ID2-s2.0-85146452039
Özet This study aimed to determine the pharmacokinetics and pharmacokinetic interaction between oxfendazole (7.5 mg/kg) and oxyclozanide (15 mg/kg) tablet formulation administered either alone or co-administered to goats orally. The study was carried out to the cross-over design into three periods, with a washout period of 21 days among administrations, on six healthy Alpine goats 1 year of age. The plasma concentrations of oxfendazole, oxfendazole metabolites fenbendazole and fenbendazole sulfone, and oxyclozanide were determined using HPLC-UV, and data were analyzed by the non-compartmental method. The plasma concentrations of oxfendazole were similar in both oxfendazole and combined groups. When oxfendazole was administered alone or in combination with oxyclozanide, the compounds recovered in plasma were oxfendazole, fenbendazole sulfone, and fenbendazole. Oxyclozanide did not change the plasma disposition of oxfendazole. In the oxyclozanide group, t1/2λz, Cmax, Tmax, and AUC0-∞ were estimated at 15.3 h, 11.6 µg/mL, 24 h, and 554 h × µg/mL, respectively. In the oxyclozanide plus oxfendazole treatment group, AUC0-∞ (1111 h×µg/mL), and Cmax (23.9 µg/mL) values were increased. In goats, the anthelmintic efficacy of oxfendazole and oxyclozanide should be determined by taking into account their pharmacokinetic data.

Yazarlar (7)

1
Zeynep Ozdemir Kutahya
2
H. Eser Faki
3
Sinan Kandir
4
Kamil Üney
ORCID: 0000-0002-8674-4873
5
B. Traş
6
Mehmet Celik
7
Osman Torun

Anahtar Kelimeler

Goat Interaction Oral Oxfendazole Oxyclozanide Pharmacokinetics

Kurumlar

Çukurova Üniversitesi
Adana Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Small Ruminant Research
Q2
SJR Skoru0,432
H-Index106
YayıncıElsevier B.V.
ÜlkeNetherlands
Animal Science and Zoology (Q2)
Food Animals (Q2)
Dergi sayfasına git

Metrikler

1
Atıf
7
Yazar
6
Anahtar Kelime

Sistemimizdeki Yazarlar

KÜ
KAMİL ÜNEY
Prof. Dr.

Hızlı Erişim

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