Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus
Acta Veterinaria · Mart 2023
YÖKSİS Kayıtları
Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus
Acta Veterinaria-Beograd · 2023 SCI-Expanded
PROFESÖR MAHMUT OK →
Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus
Acta Veterinaria Beograd · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ TUĞBA MELİKE PARLAK →
Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus
Acta Veterinaria-Beograd · 2023 SCI-Expanded
PROFESÖR MAHMUT OK →
Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus
Acta Veterinaria-Beograd · 2023 SCI-Expanded
PROFESÖR KAMİL ÜNEY →
Makale Bilgileri
DergiActa Veterinaria
Yayın TarihiMart 2023
Cilt / Sayfa73 · 22-40
Scopus ID2-s2.0-85150158198
Erişim🔓 Açık Erişim
Özet
Feline coronavirus (FCoV) infections occur commonly in cats, with entrocyte and monocyte-macrophage tropism. Most FCoV-infected cats remain asymp tomatic, but up to 10% develop fatal feline infectious peritonitis (FIP). This study aims to investigate the diagnostic utility of clinical and laboratory examinations including serum and effusion AGP levels in cats either with symptomatic effusive FIP or asymptomatic feline enteric coronavirus (FECV). The study included 40 cats with effusive FIP and 10 cats with FECV infection. The FIP group was divided into two subgroups: Abdominal (AE; n=30) and thoracic effusion (TE; n=10). Clinical and laboratory examinations, including serum or effusion AGP measurement, were performed. Among all the groups, TE group had higher body temperature, heart and respiratory rates (P<0.000). Compared with the FECV group, the FIP group had lower pH and HCO3 levels and higher base excess and lactate levels (P<0.05). The leukocyte and lymphocyte counts were higher and the hematocrit was lower in the AE group among all the groups (P<0.023). MCV was lower in the FIP group compared to the FECV group (P<0.002). In the AE group, total protein level was the lowest and the AST, GGT, total bilirubin and cholesterol levels were the highest (P<0.032) among all the groups. Magnesium level was lower in the FIP group compared to the FECV group (P<0.044). Although the serum AGP level was highest in the TE group among all groups (P<0.004), the AGP levels of cats with FECV were similar to the AE group (P>0.05). Since FECV-positive cats will likely develop FIP, differences in clinical and laboratory findings in FECV-positive cats were identified. Among them, pH, HCO3, base excess, lactate, MCV and magnesium were found to be important in the course of the disease, and AGP in the evaluation of the presence of an inflammatory state. It was concluded that clinical, laboratory and serum AGP evaluation could be used in the index of suspicion of development of FIP and FECV.
Yazarlar (6)
1
Erdem Gülersoy
ORCID: 0000-0001-8511-0150
2
M. Ok
3
Kamil Üney
ORCID: 0000-0002-8674-4873
4
Murat Kaan Durgut
5
T. M. Parlak
6
Yusuf Emre Ekici
Anahtar Kelimeler
diagnosis
Feline enteric coronavirus
feline infectious peritonitis
hematology
serum biochemistry
Kurumlar
Harran Üniversitesi
Sanliurfa Turkey
Selçuk Üniversitesi
Selçuklu Turkey