Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Evaluation of intestinal damage biomarkers in calves with atresia coli
Journal of Veterinary Research (Poland) · Ocak 2018
YÖKSİS Kayıtları
Evaluation of intestinal damage biomarkers in calves with atresia coli
Journal of Veterinary Research · 2018 SCI-Expanded
PROFESÖR MAHMUT OK →
Evaluation of intestinal damage biomarkers in calves with atresia coli
Journal of Veterinary Research · 2018 SCI-Expanded
DOÇENT MERVE İDER →
Evaluation of intestinal damage biomarkers in calves with atresia coli
Journal of Veterinary Research · 2018 SCI-Expanded
DOÇENT AMİR NASERİ →
Makale Bilgileri
DergiJournal of Veterinary Research (Poland)
Yayın TarihiOcak 2018
Cilt / Sayfa62 · 379-384
Scopus ID2-s2.0-85063146247
Erişim🔓 Açık Erişim
Özet
Intestinal obstruction such as atresia coli causes pathophysiological changes in gastrointestinal tissue due to the rise of intra-abdominal pressure. The aim of this study is to determine the intestinal damage with intestinal biomarkers in calves with atresia coli. The study was conducted on 40 Holstein calves diagnosed with atresia coli with mild to moderate abdominal distention and 10 healthy Holstein calves which served as the control. Blood samples were collected from all calves, and then serum concentrations of intestinal biomarkers were estimated, namely intestinal fatty acid binding protein (IFABP), liver fatty acid binding protein (LFABP), trefoil factor 3 (TFF3), and intestinal alkaline phosphatase (IAP), using commercially available specific bovine ELISA kits. An automatic blood gas analyser was employed for determining the lactate concentration. The concentrations of serum LFABP (P < 0.01), IFABP, TFF3, IAP, and blood lactate (P < 0.001) were significantly higher in calves with atresia coli than in healthy calves. The calves affected with atresia coli exhibited severe intestinal damage, and IFABP, LFABP, and TFF3 have significant diagnostic importance and play a useful role in determining the intestinal damage due to intestinal obstruction. High levels of IAP and lactate may serve as a signal for the development of intestinal injury.
Yazarlar (7)
1
Ramazan Yildiz
2
M. Ok
3
Merve Ider
ORCID: 0000-0003-2928-5452
4
Ugur Aydogdu
5
Amir Naseri
6
Kurtuluş Parlak
ORCID: 0000-0002-8656-037X
7
Erdem Gülersoy
ORCID: 0000-0001-8511-0150
Anahtar Kelimeler
atresia coli
calves
IFABP
LFABP
TFF3
Kurumlar
Balikesir Üniversitesi
Balikesir Turkey
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
8
Atıf
7
Yazar
5
Anahtar Kelime