Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · Ocak 2021
YÖKSİS Kayıtları
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · 2021 Scopus
PROFESÖR YAVUZ BAĞCI →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · 2021 Index Copernicus, DOAJ, EBSCOHOST databases
PROFESÖR YAVUZ BAĞCI →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz
subsp. karamanica B. Dogan & A. Duran extracts obtained with different
extraction methods
International Journal of Secondary Metabolite 2021, Vol. 8, No. 4, 389–397 · 2021 Scopus
ARAŞTIRMA GÖREVLİSİ TUĞSEN BÜYÜKYILDIRIM →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · 2021 Index Copernicus, DOAJ, EBSCOHOST databases
DOÇENT FATMA AYAZ →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · 2021 TR DİZİN
PROFESÖR NURANİYE ERUYGUR →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz
subsp. karamanica B. Dogan & A. Duran extracts obtained with different
extraction methods
International Journal of Secondary Metabolite 2021, Vol. 8, No. 4, 389–397 · 2021 Scopus
PROFESÖR YAVUZ BAĞCI →
Biological activity studies on Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran extracts obtained with different extraction methods
International Journal of Secondary Metabolite · 2021 TR DİZİN
PROFESÖR YAVUZ BAĞCI →
Makale Bilgileri
DergiInternational Journal of Secondary Metabolite
Yayın TarihiOcak 2021
Cilt / Sayfa8 · 389-397
Scopus ID2-s2.0-85164442281
Erişim🔓 Açık Erişim
Özet
The aim of this study was to investigate the antioxidant and enzyme inhibition activities of methanol extracts prepared from Klasea serratuloides (DC) Greuter & Wagenitz subsp. karamanica B. Dogan & A. Duran with Soxhlet, ultrasonic extraction, and maceration methods. 1, 1-Diphenyl-2-picryl hydroxyl (DPPH) quenching assay and 2, 2'-azinobis-3- ethylbenzothiozoline-6-sulfonic acid (ABTS) cation decolorization test were used to evaluate in vitro radical scavenging activity. The total phenolic content was determined with the Folin-Ciocalteu method while the total flavonoid content was evaluated by the aluminum chloride colorimetric method. According to the results, DPPH, ABTS radical scavenging activity and iron chelating activity of methanol of Klasea serratuloides were shown concentration-dependent manner. The extract obtained from maceration was found to be higher than the other extracts. It suggests that the maceration technique was more effective than the other extraction methods for the determination of the phenolic content. The methanol extract of KS using soxhlet (61.17 ± 3.62) and ultrasonic extraction (58.76 ± 1.46) showed higher inhibition than the extract prepared with maceration methods (34.54 ± 0.73) against BChE. All extracts displayed moderate inhibition activity against AChE. As for enzyme inhibition activity, the extract from soxhlet method was found to be more potent tyrosinase, acetylcholinesterase and butyrylcholinesterase inhibitors than the other extracts prepared by ultrasound assisted extraction and maceration methods. The present study suggests that K. serratuloides should be given special attention to conduct further investigation for its phytochemical constituents that attribute to their antioxidant potentials, and enzyme inhibition activities.
Yazarlar (6)
1
Nuraniye Eruygur
2
Fatma Ayaz
3
Yavuz Bağci
4
Süleyman Doğu
5
Tuğsen Doğru
6
Merve Kocak
ORCID: 0000-0001-7590-7190
Anahtar Kelimeler
Acetylcholinesterase
Antioxidant
Butyrylcholinesterase
Klasea serratuloides
Tyrosinase
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
1
Atıf
6
Yazar
5
Anahtar Kelime