Scopus
YÖKSİS Eşleşti
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
International Journal of Environmental Health Research · Ocak 2024
YÖKSİS Kayıtları
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
International Journal of Environmental Health Research · 2024 SCI-Expanded
DOÇENT NEVİN TUZCU →
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
International Journal of Environmental Health Research · 2024 SCI-Expanded
PROFESÖR NURANİYE ERUYGUR →
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH · 2024 SCI-Expanded
DOÇENT NEVİN TUZCU →
Phytochemical characterization and biological activities of Inula viscosa L. Aiton: a promising plant from Turkey
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH · 2024 SCI-Expanded
PROFESÖR OSMAN TUGAY →
Makale Bilgileri
DergiInternational Journal of Environmental Health Research
Yayın TarihiOcak 2024
Cilt / Sayfa34 · 3334-3347
Scopus ID2-s2.0-85182836311
Özet
The methanol extract of Inula viscosa (IVM) was investigated for its antioxidant potential using the DPPH and ABTS radical scavenging as well as iron chelating assays (ICA). The total phenol (TPC) and flavonoid contents (TFC) of IVM were determined using the Folin-Ciocalteu and aluminum trichloride methods, respectively. Antimicrobial activity of different concentrations of I. viscosa methanol extract was investigated by disc diffusion and broth microdilution method. The IVM extract was found to be containing TPC (236.78 ± 7.63 mg GAE/g) and TFC (94.36 ± 1.86 mg QE/g). Antioxidant activity IC50 values for the DPPH, ABTS and ICA assays were found to be 277.7 ± 3.68, 2.44 ± 0.02, and 222.1 ± 0.71 µg/mL, respectively. The MIC values of the IVM on the tested microorganisms ranged from 0.48 to 7.81 mg/mL. Furthermore, IVM extract was demonstrated 18.32 ± 1.37%, 23.06 ± 1.05%, 4.72 ± 0.13%, 15.13 ± 0.37% and 37.64 ± 4.02% inhibition against tyrosinase, α-amylase, α-glucosidase, AChE and BChE, respectively. In the results of LC-MS/MS analysis, acacetin, quercetin, chlorogenic acid and protocatechuic acid were determined as most dominant compounds. These findings suggested that this plant may be a natural resource for creating novel medicinal compounds.
Yazarlar (5)
1
Nuraniye Eruygur
2
Nevin Tuzcu
ORCID: 0000-0001-5899-3955
3
Osman Tugay
4
Mustafa Abdullah Yılmaz
5
Oguz Cakir
ORCID: 0000-0002-8006-2054
Anahtar Kelimeler
antimicrobial
antioxidant
enzyme inhibition
Inula viscosa
LC-MS/MS
Kurumlar
Dicle Üniversitesi
Diyarbakir Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
5
Yazar
5
Anahtar Kelime