Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Simultaneous and accurate determination of water- and fat-soluble vitamins in multivitamin tablets by using an RP-HPLC method
Quimica Nova · Ekim 2013
YÖKSİS Kayıtları
Simultaneous and accurate determination of water and fat soluble vitamins in multivitamin tablets by using an RP HPLC method
Química Nova · 2013 SCI-Expanded
PROFESÖR HAMİDE FİLİZ AYYILDIZ →
Makale Bilgileri
DergiQuimica Nova
Yayın TarihiEkim 2013
Cilt / Sayfa36 · 1044-1051
Scopus ID2-s2.0-84884748742
Erişim🔓 Açık Erişim
Özet
In the present study, a reversed-phase high-performance liquid chromatographic (RP-HPLC) procedure was developed and validated for the simultaneous determination of seven water-soluble vitamins (thiamine, riboflavin, niacin, cyanocobalamin, ascorbic acid, folic acid, and p-aminobenzoic acid) and four fat-soluble vitamins (retinol acetate, cholecalciferol, α-tocopherol, and phytonadione) in multivitamin tablets. The linearity of the method was excellent (R2 > 0.999) over the concentration range of 10-500 ng mL-1. The statistical evaluation of the method was carried out by performing the intra- and inter-day precision. The accuracy of the method was tested by measuring the average recovery; values ranged between 87.4% and 98.5% and were acceptable quantitative results that corresponded with the label claims.
Yazarlar (4)
1
Semahat Kucukkolbasi
2
Onur Bilber
3
Hamide Filiz Ayyildiz
4
Huseyin Kara
Anahtar Kelimeler
RP-HPLC
Simultaneous determination
Water-soluble and fat-soluble vitamins
Kurumlar
National Food Reference Laboratory
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
21
Atıf
4
Yazar
3
Anahtar Kelime