Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
Botanica Serbica · Ocak 2022
YÖKSİS Kayıtları
Investigation of phenolic compounds, in vitro antioxidant and enzyme
inhibition activities of methanol and aqueous extracts of different parts of
Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
PROFESÖR YAVUZ BAĞCI →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
National Library of Serbia · 2022 SCI-Expanded
PROFESÖR HAMİDE FİLİZ AYYILDIZ →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
National Library of Serbia · 2022 SCI-Expanded
PROFESÖR YAVUZ BAĞCI →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
PROFESÖR YAVUZ BAĞCI →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
PROFESÖR YAVUZ BAĞCI →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
DOÇENT FATMA AYAZ →
Investigation of phenolic compounds, in vitro antioxidant and enzyme inhibition activities of methanol and aqueous extracts of different parts of Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
PROFESÖR NURANİYE ERUYGUR →
Investigation of phenolic compounds, in vitro antioxidant and enzyme
inhibition activities of methanol and aqueous extracts of different parts of
Glaucosciadium cordifolium
Botanica Serbica · 2022 SCI-Expanded
PROFESÖR ESRA MALTAŞ ÇAĞIL →
Makale Bilgileri
DergiBotanica Serbica
Yayın TarihiOcak 2022
Cilt / Sayfa46 · 239-252
Scopus ID2-s2.0-85141279557
Erişim🔓 Açık Erişim
Özet
The present study was designed to evaluate the biological potentials and phenolic composition of different parts of Glaucosciadium cordifolium, which is less investigated and known as a wild endemic species to Turkey. The antioxidant activity of the plant was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-Azinobis-(3-Ethylbenzthiazolin-6-Sulfonic Acid) (ABTS), iron chelating capacity, and a β-carotene / linoleic acid emulsion assay. The total phenol and flavonoid contents of the plant were determined using the Folin-Ciocalteu and aluminum chloride methods, respectively. The study of the enzyme inhibition activity of the plant was carried out for acetylcholinesterase, butyrylcholinesterase, α-glucosidase, α-amylase, and tyrosinase. The antiglycation activity of the aqueous extract of the plant was evaluated using established methods such as browning, a Nitroblue-tetrazolium (NBT) assay, the 2,4-dinitrophenyl hydrazine (DNPH) method, a Congo red assay, and fluorescent Bovine Serum Albumin (BSA). The HPLC profiling of the phenolics revealed that 18 standard phenolic compounds were found in different amounts in various extracts of the plant parts. According to our bioactivity results, the methanol extract obtained from the flower parts of the plant contained higher amounts of phenolic compounds and flavonoids, which also demonstrated the highest DPPH radical scavenging activity. In addition, the methanol extracts obtained from the leaves and roots were found to be the most active extracts against the acetylcholinesterase enzyme, as well as moderately active against the tyrosinase enzyme. The antiglycation capacity of the extract followed this order: G. cordifolium leaves > stems > roots > flower. As a result, our study indicated that G. cordifolium extracts have strong antioxidant potential, good enzyme inhibitory effects and antiglycation potential. Further studies on G. cordifolium with in vivo bioassays need to be carried out to seek the importance of the plant in pharmaceutical techniques
Yazarlar (7)
1
Nuraniye Eruygur
2
Fatma Ayaz
3
Yavuz Bağci
4
Hamide Filiz Ayyildiz
5
Esra Maltas Cagil
6
Prairna Malik
7
Ahmad Ali
Anahtar Kelimeler
Antiglycation activity
Antioxidant activity
Enzyme inhibition
Glaucosciadium cordifolium
Hplc analysis
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
University of Mumbai
Mumbai India
Metrikler
4
Atıf
7
Yazar
5
Anahtar Kelime