Scopus
YÖKSİS Eşleşti
Molecular Mechanisms of Early and Late LTP
Neurochemical Research · Şubat 2019
YÖKSİS Kayıtları
Molecular Mechanisms of Early and Late LTP
Neurochemical Research · 2019 SCI-Expanded
PROFESÖR RASİM MOĞULKOÇ →
Makale Bilgileri
DergiNeurochemical Research
Yayın TarihiŞubat 2019
Cilt / Sayfa44 · 281-296
Scopus ID2-s2.0-85058084252
Özet
LTP is the most intensively studied cellular model of the memory and generally divided at least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates biochemical events and trafficking of proteins, which eventually potentiate synaptic transmission, and is independent of de novo protein synthesis. In contrast, L-LTP requires gene expression and local protein synthesis regulated via TrkB receptor- and functional prions CPEB2-3-mediated translation. Maintenance of LTP for longer periods depends on constitutively active PKMζ. Throughout this review, current knowledge about early and late phases of LTP will be reviewed.
Yazarlar (3)
1
Saltuk Bugra Baltaci
2
Rasim Mogulkoc
3
Abdulkerim Kasim Baltaci
Anahtar Kelimeler
Cpeb
Functional prions
Learning and memory
Ltp
Pkm zeta
Synaptic plasticity
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
94
Atıf
3
Yazar
6
Anahtar Kelime