Scopus
YÖKSİS Eşleşti
Effects of Tumor Volume on Lymph Node Involvement and Prognosis at Stage pt3 Colon Cancers
Indian Journal of Surgery · Şubat 2022
YÖKSİS Kayıtları
Effects of Tumor Volume on Lymph Node Involvement and Prognosis at Stage pt3 Colon Cancers
Indian Journal of Surgery · 2022 SCI-Expanded
DOÇENT HALİL ÖZER →
Makale Bilgileri
DergiIndian Journal of Surgery
Yayın TarihiŞubat 2022
Cilt / Sayfa84 · 131-135
Scopus ID2-s2.0-85104854289
Özet
Some studies showed that the increase of tumor size has a negative effect on survival in colon cancers. Our study aims to assess the effects of tumor volume on lymph node positivity and prognosis in stage pT3 colon cancers. All patients who underwent surgery for colon cancer in our clinic were evaluated retrospectively. The study included 213 patients who were diagnosed with colon adenocarcinoma and reported as pathologic. Preoperative abdomen computed tomography scans were used for measurements of tumor volume. Tumor volumes were compared according to the pathological lymph node involvement. Cut-off values were determined with ROC analysis. The cases were divided into groups according to the determined cut-off value and data compared. Mean tumor volume was found to be higher in the lymph node-positive group (p=0.01). The higher number of removed lymph nodes and lymph node positivity was detected more in cases that were above the cut-off value (p=0.003 and p=0.004, respectively). The mean survival time was 37.3±1.3 months. There was no correlation between tumor volume and the overall survival time (p=0.21). According to data comparison of the lymph node positivity, Kaplan-Meier analysis showed that the increase of the N stage reduces the 5-year survival rate (for the N0, N1, N2 stages, 60%, 52%, 35%, respectively). Tumor volume is correlated with lymph node involvement. It has been shown that increasing the N stage has a negative effect on prognosis. Our study showed that tumor volume has no significant impact on survival but may have an indirect effect on prognosis.
Yazarlar (6)
1
Mustafa Şentürk
ORCID: 0000-0002-3230-1743
2
Halil Özer
ORCID: 0000-0003-1141-1094
3
Abdülkadir Çelik
ORCID: 0000-0002-5537-7791
4
Mehmet Aykut Yıldırım
ORCID: 0000-0001-9580-6004
5
Murat Çakır
ORCID: 0000-0001-8789-8199
6
Celalettin Vatansev
ORCID: 0000-0002-0094-1703
Anahtar Kelimeler
Colon cancer
Nodal disease
pT3 tumor
Survival
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey