Scopus
YÖKSİS Eşleşti
Evaluation of signal intensity changes in dentate nucleus and globus pallidus on magnetic resonance imaging after intrathecal gadolinium-based contrast agent administration
Clinical Imaging · Mayıs 2024
YÖKSİS Kayıtları
Evaluation of signal intensity changes in dentate nucleus and globus pallidus on magnetic resonance imaging after intrathecal gadolinium-based contrast agent administration
Clinical Imaging · 2024 SCI-Expanded
DOÇENT HALİL ÖZER →
Evaluation of signal intensity changes in dentate nucleus and globus pallidus on magnetic resonance imaging after intrathecal gadolinium-based contrast agent administration
Clinical Imaging · 2024 SCI-Expanded
DOÇENT ABİDİN KILINÇER →
Evaluation of signal intensity changes in dentate nucleus and globus pallidus on magnetic resonance imaging after intrathecal gadolinium-based contrast agent administration
Clinical Imaging · 2024 SCI-Expanded
DOÇENT HAKAN CEBECİ →
Makale Bilgileri
DergiClinical Imaging
Yayın TarihiMayıs 2024
Cilt / Sayfa109
Scopus ID2-s2.0-85189554663
Özet
Purpose: Gadolinium deposition has been reported in several normal anatomical structures in the brain after repeated administration of intravenous gadolinium-based contrast agents (GBCAs) used in magnetic resonance imaging (MRI). This study presents preliminary results to see if there is any gadolinium deposition in the dentate nucleus and globus pallidus after using intrathecal GBCAs. Methods: Between November 2018 and November 2020, 29 patients who underwent intrathecal contrast-enhanced MR cisternography with the suspicion of rhinorrhea were included in this prospective study. In contrast-enhanced MR cisternography, gadoterate meglumine was administered by intrathecal injection at a dose of 1 ml. One month later, patients had a control MRI with 3D T1 SPACE fat-saturated (FS) and susceptibility weighted images (SWI) sequences. The ratio of dentate nucleus signal intensity to middle cerebellar peduncle signal intensity (DN/MCP ratio) and the ratio of globus pallidus signal intensity to thalamus signal intensity (GP/T ratio) were calculated using region of interest (ROI) on pre-contrast and control MRI sequences. Results: There was no significant difference for DN/MCP ratio and GP/T ratio on 3D T1 SPACE FS and SWI sequences after intrathecal GBCAs administration compared to baseline MRI. Conclusion: Administration of intrathecal GBCAs did not cause a measurable change in the signal intensity of the dentate nucleus and globus pallidus after a single injection.
Yazarlar (5)
1
Semih Asoğlu
2
Abidin Kılınçer
3
Halil Özer
ORCID: 0000-0003-1141-1094
4
Ömer Faruk Topaloglu
5
Hakan Cebeci
Anahtar Kelimeler
Gadolinium-based contrast agent
Gadolinium deposition
Intrathecal
Magnetic resonance imaging
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey