Scopus
YÖKSİS Eşleşti
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactions in the Presence of Water
Russian Journal of General Chemistry · Kasım 2022
YÖKSİS Kayıtları
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactions in the Presence of Water
Russ J Gen Chem · 2022 SCI
PROFESÖR MUSTAFA YILMAZ →
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactions in the Presence of Water
Russian Journal of General Chemistry · 2022 SCI-Expanded
DOÇENT ARZU UYANIK →
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactions in the Presence of Water
Russian Journal of General Chemistry · 2022 SCI-Expanded
PROFESÖR ÖZLEM ŞAHİN →
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactionsin the Presence of Water
Russian Journal of General Chemistry · 2022 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ İBRAHİM UYANIK →
Effect of Calix[4]arene as a Hydrophobic Substituent on Proline Catalysis of Direct Asymmetric Aldol Reactions in the Presence of Water
Russian Journal of General Chemistry · 2022 SCI-Expanded
PROFESÖR EZGİ AKCEYLAN →
Makale Bilgileri
DergiRussian Journal of General Chemistry
Yayın TarihiKasım 2022
Cilt / Sayfa92 · 2390-2399
Scopus ID2-s2.0-85143800663
Özet
Abstract: A new organocatalyst trans-4-hydroxy-L-proline-derived calix[4]arene was synthesized and its catalyst performance for the direct asymmetric aldol reactions between cyclohexanone and different aromatic aldehydes was investigated. The effect of a series of reaction conditions such as solvent, water and additives were evaluated in detail, and it was observed that the addition of water had a big effect on the enantioselectivities. Specifically, high anti-diastereoselectivity (anti/syn = 92 : 8) and high enantioselectivity (ee 88%) were obtained from the reaction between cyclohexanone and 4-fluorobenzaldehyde in the presence of water.
Yazarlar (6)
1
Arzu Uyanik
2
Ozlem Sahin
3
Ezgi Akceylan
4
S. Eymur
ORCID: 0000-0003-3346-6010
5
I. Uyanik
ORCID: 0000-0002-1028-8293
6
Mustafa Yilmaz
Anahtar Kelimeler
calix[4]arene
direct asymmetric aldol reaction
L-proline
organocatalysis
Kurumlar
Giresun Üniversitesi
Giresun Turkey
Selçuk Üniversitesi
Selçuklu Turkey