Scopus
YÖKSİS Eşleşti
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.-Mor
Chemistry and Biodiversity · Haziran 2023
YÖKSİS Kayıtları
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
Chemistry & Biodiversity · 2023 SCI-Expanded
ARAŞTIRMA GÖREVLİSİ TUĞSEN BÜYÜKYILDIRIM →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
Chemistry & Biodiversity · 2023 SCI-Expanded
DOÇENT FATMA AYAZ →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
Chemistry and Biodiversity · 2023 SCI-Expanded
PROFESÖR NURANİYE ERUYGUR →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
Chemistry and Biodiversity · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ ŞEYMA TETİK RAMA →
Phytochemical Profiling and Biological Activity of Achillea sintenisii Hub.‐Mor
Chemistry & Biodiversity · 2023 SCI-Expanded
PROFESÖR MEHMET TUZCU →
Makale Bilgileri
DergiChemistry and Biodiversity
Yayın TarihiHaziran 2023
Cilt / Sayfa20
Scopus ID2-s2.0-85159642321
Özet
Achillea (Asteraceae) species have been traditionally used for their different therapeutical properties. In this study, phytochemical composition of aerial parts of A. sintenisii which is endemic in Turkey was determined with Liquid chromatography/mass spectrometry/mass spectrometry (LC/MS/MS). To evaluate the wound healing potential, the cream formulation prepared from A. sintenisii was tested on the linear incision wound model in mice. In vitro enzyme inhibitory activity tests were performed on elastase, hyaluronidase, and collagenase. In the histopathological examination, angiogenesis and granulation tissue formation were significantly increased in A. sintenisii treatment groups compared to the negative control group. As a result of this study, it is thought that the enzyme inhibition and antioxidant activity of the plant may contribute to the wound healing process. According to LC/MS/MS analysis result, quinic acid (24.261 μg/mg extract) and chlorogenic acid (14.97 μg/mg extract) were identified as main constituents of the extract.
Yazarlar (8)
1
Nuraniye Eruygur
2
Tugsen Buyukyildirim
3
Seyma Tetik Rama
4
Fatma Ayaz
5
Mehmet Tekin
6
Mehmet Tuzcu
7
G. Akcakavak
8
Mustafa Abdullah Yılmaz
Anahtar Kelimeler
Achillea sintenisii
in vitro
in vivo
LC/MS/MS
wound healing
Kurumlar
Bozok Üniversitesi
Yozgat Turkey
Dicle Üniversitesi
Diyarbakir Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Trakya Üniversitesi
Edirne Turkey
Metrikler
3
Atıf
8
Yazar
5
Anahtar Kelime