Scopus
Rapid and real-time detection of arginine enantiomers by QCM sensor having a Calix[4]arene receptor bearing asymmetric centers
Talanta · Kasım 2019
Makale Bilgileri
DergiTalanta
Yayın TarihiKasım 2019
Cilt / Sayfa204 · 172-181
Scopus ID2-s2.0-85066329074
Özet
This paper describes the sensing studies of a chiral calix[4]arene receptor (5)having (R)-2-phenylglycinol moiety for arginine enantiomers (D-/L-arginine)by using Quartz Crystal Microbalance (QCM)technique. The initial experiments have revealed that the chiral calix[4]arene 5 coated QCM (CCC-QCM)sensor showed good sensing for arginine enantiomers, such that it has exhibited higher sensing towards D-arginine than that of L-arginine. It has been determined that the sensitivity, limit of detection values of CCC-QCM sensor for the D-/L-arginine solutions as 0.024/0.023 Hz/μM and 0.38/1.29 μM, respectively. On the other hand, the racemic mixture studies were optimized using the response surface methodology with central composite design. Consequently, it has been demonstrated that the QCM sensor modification with a calix[4]arene receptor bearing asymmetric centers provided rapid, real-time, sensitive and effective sensing of arginine enantiomers.
Yazarlar (5)
1
Farabi Temel
2
Serkan Erdemir
ORCID: 0000-0003-0790-0549
3
Egemen Ozcelik
4
Begum Tabakci
5
Mustafa Tabakci
Anahtar Kelimeler
Amino acid
Arginine
Calixarene
Quartz crystal microbalance
Sensing
Sensor
Kurumlar
Konya Technical University
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
21
Atıf
5
Yazar
6
Anahtar Kelime