Scopus
YÖKSİS Eşleşti
Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution
Talanta · Aralık 2022
YÖKSİS Kayıtları
Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution
Talanta · 2022 SCI-Expanded
PROFESÖR EZGİ AKCEYLAN →
Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution
TALANTA · 2022 SCI-Expanded
PROFESÖR ABDULLAH SİVRİKAYA →
Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution
TALANTA · 2022 SCI-Expanded
PROFESÖR BEGÜM TABAKCI →
Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution
Talanta · 2022 SCI-Expanded
PROFESÖR SERKAN ERDEMİR →
Makale Bilgileri
DergiTalanta
Yayın TarihiAralık 2022
Cilt / Sayfa250
Scopus ID2-s2.0-85134427417
Özet
A switchable fluorescence sensor based on a calix (Monapathi et al., 2021) [4]arene:Cu2+ complex (FLCX/Cu) has been developed for the detection of itraconazole (ITZ) with high sensitivity and specificity. For the development of the sensor, the selective complexation of a fluorescent calix (Monapathi et al., 2021) [4]arene derivative (FL-CX) with the Cu2+ ion causing fluorescence quenching was utilized. In addition, the sensor properties of the FLCX/Cu prepared were investigated. For this purpose, various substances (selected anions, cations, and drugs) with which ITZ can be found together were studied in an aqueous solution. Limit of detection (LOD) and limit of quantification (LOQ) values were determined in the range of 1.00–60.0 μg/L as 3.34 μg/L and 11.1 μg/L for ITZ, respectively. Moreover, the real sample analyses were performed in human serum and tablet form. Furthermore, the effect of some possible serum contents on sensor performance was also studied. All these studies confirmed the development of a simple, precise, accurate, reproducible, highly sensitive, and very stable fluorescence sensor.
Yazarlar (5)
1
Ezgi Akceylan
2
Serkan Erdemir
ORCID: 0000-0003-0790-0549
3
Mustafa Tabakci
4
Abdullah Sivrikaya
5
Begum Tabakci
Anahtar Kelimeler
Calixarene
Fluorescence sensor
Human serum
Itraconazole
Pharmaceutical
Kurumlar
Konya Technical University
Konya Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
4
Atıf
5
Yazar
5
Anahtar Kelime