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The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum

Journal of the Science of Food and Agriculture · Mart 2024

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YÖKSİS Kayıtları
The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum
Journal of the Science of Food and Agriculture · 2024 SCI-Expanded
ARAŞTIRMA GÖREVLİSİ FATMA NUR ALP TURGUT →
The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum
Journal of the Science of Food and Agriculture · 2024 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
The exogenous application of naringenin and rosmarinic acid modulates functional traits in Lepidium sativum
Journal of the Science of Food and Agriculture · 2024 SCI-Expanded
DOÇENT BÜŞRA ARIKAN ABDULVELİ →

Makale Bilgileri

DergiJournal of the Science of Food and Agriculture
Yayın TarihiMart 2024
Cilt / Sayfa104 · 2761-2771
Erişim🔓 Açık Erişim
Özet BACKGROUND: Phenolic modulators have attracted attention for their potential in shaping functional traits in plants. This work investigated the impact of naringenin (Nar) and rosmarinic acid (RA) on the functional properties of Lepidium sativum leaves and roots. Results: Untargeted metabolomics identified a diverse phenolic profile, including flavonoids, phenolic acids, low molecular weight phenolics, lignans, and stilbenes. Cluster, analysis of variance multiblock orthogonal partial least squares (AMOPLS), and orthogonal projection to latent structures discriminant analysis (OPLS-DA) multivariate analyses confirmed tissue-specific modulation of bioactive compounds. The tissue was the hierarchically most influential factor, explaining 27% of observed variability, while the treatment and their interaction were statistically insignificant. Thereafter, various in vitro assays were employed to assess antioxidant capacity, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) radical scavenging activity, cupric ion reducing antioxidant capacity (CUPRAC), and ferric ion reducing antioxidant power (FRAP), metal chelating ability, and phosphomolybdenum (PMD) assays. Extracts were also tested for inhibitory effects on cholinesterase, amylase, glucosidase, and tyrosinase enzymes. RA application positively impacted antioxidant and enzyme inhibitory activities, holding valuable implications in shaping the health-promoting properties of L. sativum. Conclusion: The untargeted metabolomics analysis showed a significant tissue-dependent modulation of bioactive compounds, determining no synergistic effect between applying phenolic compounds in combination. Specifically, the sole application of RA increased anthocyanins and hydroxyphenyl propanoic acid content on leaves, which was strictly related to enhancing the biological activities. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Yazarlar (10)

1
Hajar Salehi
2
Leilei Zhang
ORCID: 0000-0002-9278-0459
3
Fatma Nur Alp-Turgut
ORCID: 0000-0002-1884-2367
4
Busra Arikan
ORCID: 0000-0001-5313-0501
5
Fevzi Elbasan
6
Ceyda Ozfidan-Konakci
ORCID: 0000-0002-7134-0948
7
Melike Balci
8
Gokhan Zengin
ORCID: 0000-0001-6548-7823
9
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
10
Luigi Lucini
ORCID: 0000-0002-5133-9464

Anahtar Kelimeler

bioactive constituents chemometrics elicitors functional foods nutraceutical phenolic profiling

Kurumlar

Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Università Cattolica del Sacro Cuore, Campus di Piacenza e Cremona
Piacenza Italy

Metrikler

1
Atıf
10
Yazar
6
Anahtar Kelime