Scopus
YÖKSİS Eşleşti
Sideritis galatica Bornm.: A source of multifunctional agents for the management of oxidative damage, Alzheimer's's and diabetes mellitus
Journal of Functional Foods · Ocak 2014
YÖKSİS Kayıtları
Sideritis galatica Bornm A source of multifunctional agents for the management of oxidative damage Alzheimer s s and diabetes mellitus
Journal of Functional Foods · 2014 SCI-Expanded 1 atıf
PROFESÖR GÖKHAN ZENGİN →
Sideritis galatica Bornm A source of multifunctional agents for the management of oxidative damage Alzheimer s s and diabetes mellitus
Journal of Functional Foods · 2014 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Makale Bilgileri
DergiJournal of Functional Foods
Yayın TarihiOcak 2014
Cilt / Sayfa11 · 538-547
Scopus ID2-s2.0-84926419780
Özet
The antioxidant and enzyme inhibitory potential of different solvent extracts (petroleum ether, ethyl acetate, methanol and water) from Sideritis galatica were evaluated. Cholinesterase, α-amylase and α-glucosidase inhibitory activities of the extracts were tested by microtiter plate assays. Antioxidant abilities were tested using free radical scavenging (DPPH (1,1-diphenyl-2-picrylhydrazyl), ABTS (2,2'-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid) and NO), reducing power (FRAP (ferric reducing antioxidant power) and CUPRAC (cupric reducing antioxidant capacity)), total antioxidant capacity and chelating assays. Methanol and water extracts showed higher phenolic content, DPPH and ABTS scavenging activity and reducing power activities, while the petroleum ether and ethyl acetate extract had the highest inhibition abilities on the enzymes. 18 phenolic components in these extracts were detected by using high performance liquid chromatography-diode array detector (HPLC-DAD). Results obtained in this work indicate that S. galatica may be useful as a source of natural agents for the management of oxidative process, Alzheimer's disease and type II diabetes.
Yazarlar (4)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Cengiz Sarikurkcu
3
Abdurrahman Aktumsek
4
Ramazan Ceylan
Anahtar Kelimeler
Alzheimer's
Antioxidant
Diabetes
HPLC
Sideritis galatica
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Metrikler
105
Atıf
4
Yazar
5
Anahtar Kelime