Scopus
Antioxidant potential and inhibition of key enzymes linked to Alzheimer’s diseases and diabetes mellitus by monoterpene-rich essential oil from Sideritis galatica Bornm. Endemic to Turkey
Records of Natural Products · Ağustos 2015
Makale Bilgileri
DergiRecords of Natural Products
Yayın TarihiAğustos 2015
Cilt / Sayfa10 · 195-206
Scopus ID2-s2.0-84938798165
Özet
The present study was designated to (1) characterize the essential oil from S. galatica (SGEOs) and (2) evaluate its antioxidant and enzyme inhibitory activities. Antioxidant capacity was tested different methods including free radical scavenging (DPPH, ABTS and NO), reducing power (FRAP and CUPRAC), metal chelating and phosphomolybdenum. Inhibitory activities were analyzed on acetylcholiesterase, butrylcholinesterase, α-amylase and α-glucosidase. SGEOs were chemically analyzed and identified by gas chromatography and gas chromatography/mass spectrophotometry. 23 components, representing 98.1% of SGEOs were identified. Monoterpene hydrocarbons (74.1%), especially α- (23.0%) and β-pinene (32.2%), were the main constituents in SGEOs. The main sesquiterpene hydrocarbons were β-caryophyllene (16.9%), germacrene-D (1.2%) and caryophyllene oxide (1.2%), respectively. Generally, SGEOs has shown moderate free radical, reducing power, metal chelating and enzyme inhibitory activities. These activities related to chemical profile in SGEOs. Our findings supported that the possible utility of SGEOs is a source of natural agents for food or pharmaceutical industries.
Yazarlar (4)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Cengiz Sarikurkcu
3
Abdurrahman Aktumsek
4
Ramazan Ceylan
Anahtar Kelimeler
Anti-diabetic
Antioxidants
Cholinesterase
Monoterpenes
Sideritis galatica
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Metrikler
62
Atıf
4
Yazar
5
Anahtar Kelime