Scopus
YÖKSİS Eşleşti
Crepis foetida L. subsp. rhoeadifolia (Bieb.) Celak. as a source of multifunctional agents: Cytotoxic and phytochemical evaluation
Journal of Functional Foods · Ağustos 2015
YÖKSİS Kayıtları
Crepis foetida L subsp rhoeadifolia Bieb Celak as a source of multifunctional agents Cytotoxic and phytochemical evaluation
Journal of Functional Foods · 2015 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Crepis foetida L subsp rhoeadifolia Bieb Celak as a source of multifunctional agents Cytotoxic and phytochemical evaluation
Journal of Functional Foods · 2015 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ PEMBEGÜL UYAR ARPACI →
Crepis foetida L subsp rhoeadifolia Bieb Celak as a source of multifunctional agents Cytotoxic and phytochemical evaluation
Journal of Functional Foods · 2015 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiJournal of Functional Foods
Yayın TarihiAğustos 2015
Cilt / Sayfa17 · 698-708
Scopus ID2-s2.0-84938835119
Özet
The cytotoxic, anticholinesterase, antityrosinase and antioxidant effects of methanol extract from the flower of C. foetida subsp. rhoeadifolia (CFRME) were evaluated. The cytotoxic effect was investigated using HepG2, Caco-2, MCF-7 and MCF-10A cell lines. Enzyme inhibitory activities were tested by spectrophotometric methods. Different chemical assays were used to determine the antioxidant effects. In addition, phenolic constituents were quantified. High-performance liquid chromatographic (HPLC) analysis revealed that chlorogenic acid was the major phenolic component in the extract. The extract showed a strong antiproliferative, antioxidant, and anticholinesterase and antityrosinase effects. These findings suggest that C. foetida subsp. rhoeadifolia may be considered as a source of ingredients that can be used as food supplements.
Yazarlar (7)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Cengiz Sarikurkcu
3
Pembegul Uyar
4
Abdurrahman Aktumsek
5
Sengul Uysal
6
Mehmet Sefa Kocak
7
Ramazan Ceylan
Anahtar Kelimeler
Anticholinesterase
Antioxidant effects
Antiproliferative
Antityrosinase
Crepis foetida subsp. rhoeadifolia
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Metrikler
62
Atıf
7
Yazar
5
Anahtar Kelime