Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Onosma aucheriana: A source of biologically active molecules for novel food ingredients and pharmaceuticals
Journal of Functional Foods · Aralık 2015
YÖKSİS Kayıtları
Onosma aucheriana A source of biologically active molecules for novel food ingredients and pharmaceuticals
Journal of Functional Foods · 2015 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiJournal of Functional Foods
Yayın TarihiAralık 2015
Cilt / Sayfa19 · 479-486
Scopus ID2-s2.0-84946399978
Erişim🔓 Açık Erişim
Özet
The phenolic profile, antioxidant activity and cytotoxicity of O. aucheriana aqueous extract were investigated. HPLC-DAD (high performance liquid chromatography-diode array detector) technique was used to define the profile of phenolic compounds of the resultant extract. Antioxidant properties were evaluated using different methods, including phosphomolybdenum, free radical scavenging and lipid peroxidation assays. Rosmarinic, gallic and p-hydroxybenzoic acids were determined as the major phenolic compounds. Human rhabdomyosarcoma (RD), human cervix carcinoma (Hep2c) and murine fibroblast (L2OB) cell lines were used to examine the cytotoxicity of the extract. The IC50 (inhibitory concentration at 50%) values ranged from 25.54 to 40.34 μg/mL. These results suggest that this species may be considered as a valuable candidate for preparing new food and drug formulations.
Yazarlar (7)
1
Pavle Mašković
2
Lazari D. Diamanto
3
Jelena M. Vujić
4
Aleksandra Cvetanović Kljakić
5
Marija Radojković
6
Slobodan B. Gadžurić
7
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
Antimicrobial
Antioxidant
Natural product
Onosma aucheriana
Rosmarinic acid
Kurumlar
Faculty of Health Sciences
Thessaloniki Greece
Selçuk Üniversitesi
Selçuklu Turkey
University of Kragujevac
Kragujevac Serbia
University of Novi Sad
Novi Sad Serbia
Metrikler
39
Atıf
7
Yazar
5
Anahtar Kelime