Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q1
Analysis of chromosomes 8 and 17 aneuploidies laryngeal squamous cell carcinoma by fluorescence in situ hybridization
Laryngoscope · Haziran 2004
YÖKSİS Kayıtları
Analysis of Chromosomes 8 and 17 Aneuploidies in Laryngeal Squamous Cell Carcinoma by Fluorescence In Situ Hybridization
The Laryngoscope · 2004 SCI-Expanded
Prof. Dr. HASAN ACAR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Thyroid Medullary Carcinoma in a Teenager With Cowden Syndrome
2007 ISSN: 0023-852X SCI
Prof. Dr. HANDE KÖKSAL →
Thyroid medullary carcinoma in a teenager with Cowden syndrome
2007 ISSN: 0023-852X SCI-Expanded
Prof. Dr. YAVUZ KÖKSAL →
In Reference to Association of Severe Tongue Edema With Prone Positioning in Patients Intubated for COVID-19
2022 ISSN: 0023-852X SCI-Expanded Q1
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In Reference to Association of Severe Tongue Edema With Prone Positioning in Patients Intubated for COVID-19
2022 ISSN: 0023-852X SCI-Expanded Q1
Doç. Dr. MERİH ÖNAL →
Analysis of Chromosomes 8 and 17 Aneuploidies in Laryngeal Squamous Cell Carcinoma by Fluorescence In Situ Hybridization
2004 ISSN: 0023-852X SCI-Expanded Q1
Prof. Dr. HASAN ACAR →
Glottic Opening Appearance is Not Sufficient for Every Endotracheal Intubation
2022 ISSN: 0023-852X SCI Q1
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In Reference to The Cost of Surgery is not a Simple Mathematical Calculation
2023 ISSN: 0023-852X SCI-Expanded Q2
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In Reference to Investigation of Adult Post‐Tonsillectomy Hemorrhage Rates and the Impact of NSAID Use
2023 ISSN: 0023-852X SCI-Expanded Q2
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In Reference to Predictors of Postoperative Nausea and Vomiting After Endoscopic Skull Base Surgery
2023 ISSN: 0023-852X SCI-Expanded Q2
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In Reference to A Prospective Observational Study of Video Laryngoscopy Use in Difficult Airway Management
2022 ISSN: 0023-852X SCI-Expanded Q1
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In reference to Prediction of Oxygen Desaturation by Using Sound Data From a Noncontact Device: A Proof‐of‐Concept Study
2023 ISSN: 0023-852X SCI-Expanded Q2
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
In reference to Inflammation‐Based Score Predicts Pharyngocutaneous Fistula
2023 ISSN: 0023-852X SCI-Expanded Q2
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
Glottic Opening Appearance is Not Sufficient for Every Endotracheal Intubation
2022 ISSN: 0023-852X SCI Q1
Doç. Dr. MERİH ÖNAL →
In Reference to The Cost of Surgery is not a Simple Mathematical Calculation
2023 ISSN: 0023-852X SCI-Expanded Q2
Doç. Dr. MERİH ÖNAL →
In Reference to Predictors of Postoperative Nausea and Vomiting After Endoscopic Skull Base Surgery
2023 ISSN: 0023-852X SCI-Expanded Q2
Doç. Dr. MERİH ÖNAL →
In Reference to A Prospective Observational Study of Video Laryngoscopy Use in Difficult Airway Management
2022 ISSN: 0023-852X SCI Q1
Doç. Dr. MERİH ÖNAL →
In reference to Inflammation‐Based Score Predicts Pharyngocutaneous Fistula
2023 ISSN: 0023-852X SCI-Expanded Q2
Doç. Dr. MERİH ÖNAL →
In reference to Prediction of Oxygen Desaturation by Using Sound Data From a Noncontact Device: A Proof‐of‐Concept Study
2023 ISSN: 0023-852X SCI Q2
Doç. Dr. MERİH ÖNAL →
In Reference to Investigation of Adult Post‐Tonsillectomy Hemorrhage Rates and the Impact of NSAID Use
2023 ISSN: 0023-852X SCI-Expanded Q2
Doç. Dr. MERİH ÖNAL →
Makale Bilgileri
Dergi
Laryngoscope
ISSN0023852X
Yayın TarihiHaziran 2004
Cilt / Sayfa114 · 1005-1010
Scopus ID2-s2.0-2942562289
Erişim🔓 Açık Erişim
Özet
Objectives/Hypothesis: The objectives were to investigate chromosomes 8 and 17 numerical aberrations by using fluorescence in situ hybridization in laryngeal squamous cell carcinoma and also to determine whether there is any association between chromosomes 8 and 17 aneuploidies and TNM classification and subgroups of laryngeal squamous cell carcinomas. Study Design: Descriptive study. Methods: Tumor and control samples were taken from 23 patients with LSCC by surgical operation. Fluorescence in situ hybridization analysis with chromosomes 8- and 17-specific α-satellite DNA probes was performed on the interphase nuclei. Results: The percentages for chromosomes 8 and 17 aneuploidies were 33% (SD = 25.7%) (median value, 26.2%; range, 3.5%-81.8%) and 19.2% (SD = 15.8%) (median value, 9.8%; range, 3.6%-63.7%), respectively. There was a significant difference between stage 2 and stage 3 (P < .05) and between stage 2 and stage 4 for chromosome 8 aneuploidy (P < .05) but not for chromosome 17 aneuploidy (P > .05). There was also a significant difference for the T classification for chromosome 8 aneuploidy (P < .05) but not for chromosome 17 (P > .05). Conclusion: Chromosome 8 aneuploidy may be related to stage and T classification of laryngeal squamous cell carcinoma and its progression.
Yazarlar (5)
1
Kayhan Öztürk
2
Hasan Acar
3
Ercan Durmus
ORCID: 0000-0003-4851-4230
4
Adnan Öztürk
5
Necip Mutlu
Anahtar Kelimeler
Aneuploidy
Chromosome 17
Chromosome 8
Fluorescence in situ hybridization
Laryngeal cancers
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Laryngoscope
Q1
SJR Skoru1,029
H-Index183
YayıncıWiley-Blackwell
ÜlkeUnited States
Otorhinolaryngology (Q1)
Metrikler
3
Atıf
5
Yazar
5
Anahtar Kelime