Scopus
YÖKSİS Eşleşti
GC-MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic Thymus spathulifolius Hausskn. et Velen
Journal of Enzyme Inhibition and Medicinal Chemistry · Kasım 2016
YÖKSİS Kayıtları
GC MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic Thymus spathulifolius Hausskn et Velen
Journal of Enzyme Inhibition and Medicinal Chemistry · 2015 SCI
PROFESÖR GÖKHAN ZENGİN →
GC-MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic
<i>Thymus spathulifolius</i>
Hausskn. et Velen
</title>
Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Makale Bilgileri
DergiJournal of Enzyme Inhibition and Medicinal Chemistry
Yayın TarihiKasım 2016
Cilt / Sayfa31 · 983-990
Scopus ID2-s2.0-84940488798
Özet
We investigated the antioxidant and enzyme inhibitory activities and chemical composition of the hydro-distilled essential oil (0.35% yield) from aerial parts of Thymus spathulifolius. Antioxidant capacity of the oil was assessed by different methods including free radical scavenging (DPPH and ABTS), reducing power (FRAP and CUPRAC) and phosphomolybdenum assay. Inhibitory activities were analyzed against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, and tyrosinase. Twenty-one constituents were identified representing 97.2% of the total oil with thymol (50.5%), borneol (16.7%) and carvacrol (7.7%) as the major components. The essential oil exhibited good antioxidant activity with IC50 values of 3.82 and 0.22 mg/mL determined by free radical scavenging DPPH and ABTS, respectively. EC50 values of FRAP and CUPRAC were found to be 0.12 and 0.34 mg/mL, respectively. The results of the present study support the uses of T. spathulifolius essential oil as a source of natural antioxidants and bioactivities for functional foods and phytomedicines.
Yazarlar (7)
1
Ramazan Ceylan
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Sengul Uysal
4
Veli Ilhan
5
Abdurrahman Aktumsek
6
Ali Kandemir
7
F. Anwar
Anahtar Kelimeler
Antioxidant
enzyme inhibition
thymol
Thymus spathulifolius
Kurumlar
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
Prince Sattam Bin Abdulaziz University
Al Kharj Saudi Arabia
Selçuk Üniversitesi
Selçuklu Turkey
University of Sargodha
Sargodha Pakistan
Metrikler
31
Atıf
7
Yazar
4
Anahtar Kelime