Scopus
YÖKSİS DOI Eşleşti
SJR Q2
GC-MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic Thymus spathulifolius Hausskn. et Velen
Journal of Enzyme Inhibition and Medicinal Chemistry · Kasım 2016
YÖKSİS Kayıtları
GC MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic Thymus spathulifolius Hausskn et Velen
Journal of Enzyme Inhibition and Medicinal Chemistry · 2015 SCI
Prof. Dr. GÖKHAN ZENGİN →
GC-MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic
<i>Thymus spathulifolius</i>
Hausskn. et Velen
</title>
Journal of Enzyme Inhibition and Medicinal Chemistry · 2016 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Synthesis of 3 aroyl 4 aryl 1 isopropylamino 4 piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines
2014 ISSN: 1475-6366 SCI
Prof. Dr. KAAN KÜÇÜKOĞLU →
Synthesis of 4 2 substituted hydrazinyl benzenesulfonamides and their carbonic anhydrase inhibitory effects
2016 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. KAAN KÜÇÜKOĞLU →
Anthraquinone profile antioxidant and enzyme inhibitory effect of root extracts of eight i Asphodeline i taxa from Turkey can i Asphodeline i roots be considered as a new source of natural compounds title
2016 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations
2017 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. AHMET UYSAL →
Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa
2016 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
GC-MS analysis and in vitro antioxidant and enzyme inhibitory activities of essential oil from aerial parts of endemic
<i>Thymus spathulifolius</i>
Hausskn. et Velen
</title>
2016 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Microwave-assisted synthesis and bioevaluation of new sulfonamides
2017 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. KAAN KÜÇÜKOĞLU →
Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
2020 ISSN: 1475-6366 SCI-Expanded
Prof. Dr. MUSTAFA YILMAZ →
Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization
2013 ISSN: 1475-6366 SCI
Doç. Dr. HANİF ŞİRİNZADE →
Novel indole-based melatonin analogues substituted with triazole, thiadiazole and carbothioamides: studies on their antioxidant, chemopreventive and cytotoxic activities
2016 ISSN: 1475-6366 SCI
Doç. Dr. HANİF ŞİRİNZADE →
Synthesis and evaluation of antioxidant activity of new quinoline-2-carbaldehyde hydrazone derivatives: bioisosteric melatonin analogues
2016 ISSN: 1475-6366 SCI
Doç. Dr. HANİF ŞİRİNZADE →
Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
2020 ISSN: 1475-6366 SCI-Expanded Q1
Doç. Dr. MEHMET OĞUZ →
Makale Bilgileri
ISSN14756366
Yayın TarihiKasım 2016
Cilt / Sayfa31 · 983-990
Scopus ID2-s2.0-84940488798
Özet
We investigated the antioxidant and enzyme inhibitory activities and chemical composition of the hydro-distilled essential oil (0.35% yield) from aerial parts of Thymus spathulifolius. Antioxidant capacity of the oil was assessed by different methods including free radical scavenging (DPPH and ABTS), reducing power (FRAP and CUPRAC) and phosphomolybdenum assay. Inhibitory activities were analyzed against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, and tyrosinase. Twenty-one constituents were identified representing 97.2% of the total oil with thymol (50.5%), borneol (16.7%) and carvacrol (7.7%) as the major components. The essential oil exhibited good antioxidant activity with IC50 values of 3.82 and 0.22 mg/mL determined by free radical scavenging DPPH and ABTS, respectively. EC50 values of FRAP and CUPRAC were found to be 0.12 and 0.34 mg/mL, respectively. The results of the present study support the uses of T. spathulifolius essential oil as a source of natural antioxidants and bioactivities for functional foods and phytomedicines.
Yazarlar (7)
1
Ramazan Ceylan
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Sengul Uysal
4
Veli Ilhan
5
Abdurrahman Aktumsek
6
Ali Kandemir
7
F. Anwar
Anahtar Kelimeler
Antioxidant
enzyme inhibition
thymol
Thymus spathulifolius
Kurumlar
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
Prince Sattam Bin Abdulaziz University
Al Kharj Saudi Arabia
Selçuk Üniversitesi
Selçuklu Turkey
University of Sargodha
Sargodha Pakistan
Scimago Dergi (ISSN Eşleşmesi)
Journal of Enzyme Inhibition and Medicinal Chemistry
Q2
OA
SJR Skoru0,857
H-Index98
YayıncıInforma Healthcare
ÜlkeUnited Kingdom
Drug Discovery (Q2)
Medicine (miscellaneous) (Q2)
Pharmacology (Q2)
Metrikler
35
Atıf
7
Yazar
4
Anahtar Kelime