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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q2

Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation

South African Journal of Botany · Mart 2017

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YÖKSİS Kayıtları
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
South African Journal of Botany · 2017 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
South African Journal of Botany · 2017 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
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Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
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Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
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Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
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Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
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In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
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Makale Bilgileri

ISSN02546299
Yayın TarihiMart 2017
Cilt / Sayfa109 · 50-57
Erişim🔓 Açık Erişim
Özet The present study outlines the phenolic composition of methanolic extracts of Digitalis ferruginea and Digitalis lamarckii aerial parts and evaluates their biological activities. The quantification of phenolic compounds was carried out by HPLC–DAD analysis. Antioxidant properties were assessed using different assays. Enzyme inhibition was tested on AChE, BChE, α-amylase, α-glucosidase, and tyrosinase. The antimicrobial properties of the extracts were determined using the microdilution method. Genotoxicity of the extracts was assessed on Drosophila melanogaster by comet assay. D. lamarcki extract was richer in phenolic compounds than D. ferruginea, with chlorogenic acid as dominant compound in both D. lamarckii and D. ferruginea extracts (2.99 and 1.30 mg/g, respectively). Both extracts showed similar values in terms of antioxidant activity. The extracts showed enzyme inhibitory activity on above-mentioned enzymes and moderate antimicrobial activity (MIC range 0.625–10 mg/mL). D. ferruginea extract (20 mg/mL) indicated the absence of genotoxicity, while all concentrations of D. lamarckii extract showed significant DNA damage. Antigenotoxic effect was more evident in the group treated with D. lamarckii extract, 80 mg/mL (%R = 80.3). The results emphasized the biological potential of examined plants and encourage further studies for their potential use as phytopharmaceuticals.

Yazarlar (8)

1
Jelena S. Katanić Stanković
2
Ramazan Ceylan
3
Sanja Matić
4
Tatjana Jurić
5
Gokhan Zengin
ORCID: 0000-0001-6548-7823
6
Abdurrahman Aktumsek
7
Vladimir Mihailović
8
Snežana Stanić

Anahtar Kelimeler

Antigenotoxic Antimicrobial Antioxidant Digitalis HPLC

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
University of Kragujevac
Kragujevac Serbia
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Dergi sayfasına git

Metrikler

14
Atıf
8
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar