Scopus
YÖKSİS Eşleşti
Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential
Journal of Functional Foods · Ağustos 2017
YÖKSİS Kayıtları
Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential
Journal of Functional Foods · 2017 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential
Journal of Functional Foods · 2017 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Makale Bilgileri
DergiJournal of Functional Foods
Yayın TarihiAğustos 2017
Cilt / Sayfa35 · 32-42
Scopus ID2-s2.0-85019859084
Özet
In this study, the nutraceutical potential of Capparis spinosa L. for the treatment of hyperglycemic states has been thoroughly investigated. A series of in vivo and in vitro tests have been conducted on fresh leaf, buds and salty buds (24 h desalted) processed to dry powder. 60% MeOH/H2O extracts were obtained for HPLC analysis and for α-amylase and α-glucosidase inhibition tests. To estimate the in vivo anti-diabetic effect, dry powders of C. spinosa leaf and buds were orally administered to streptozocin-induced diabetic rats over a period of 28 days. At the end of the experiment, animals were sacrificed, blood taken for assessment of lipid profile and liver/kidney biochemistry while section of the pancreas, liver and kidneys were processed for general histology. Results showed that the regular administration of C. spinosa leaf or buds normalized all the biochemical parameters and reversed the liver/kidney injury with variable degrees of organ protection.
Yazarlar (13)
1
Adriano Mollica
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Marcello Locatelli
ORCID: 0000-0002-0840-825X
4
Azzurra Stefanucci
5
Andrei Mocan
6
Giorgia Macedonio
7
Simone Carradori
8
Olakunle J. Onaolapo
9
Adejoke Y. Onaolapo
10
Juliet Adegoke
11
Marufat Olaniyan
12
Abdurrahman Aktumsek
13
Ettore Novellino
Anahtar Kelimeler
Capparis spinosa L
Diabetes
Flavonoids
HPLC
Nutraceuticals
Polyphenols
α-Amylase
α-Glucosidase
Kurumlar
Ladoke Akintola University of Technology
Ogbomoso Nigeria
Science Faculty
Konya Turkey
Università degli Studi di Napoli Federico II
Naples Italy
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
Universitatea de Stiinte Agricole si Medicina Veterinara din Cluj-Napoca
Cluj Napoca Romania
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Metrikler
130
Atıf
13
Yazar
8
Anahtar Kelime