Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Functional components, antidiabetic, anti-Alzheimer’s disease, and antioxidant activities of Salvia syriaca L.
International Journal of Food Properties · Ağustos 2017
YÖKSİS Kayıtları
Functional components, antidiabetic, anti-Alzheimer’s disease, and antioxidant activities of Salvia syriaca L.
International Journal of Food Properties · 2017 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiInternational Journal of Food Properties
Yayın TarihiAğustos 2017
Cilt / Sayfa20 · 1761-1772
Scopus ID2-s2.0-85004000367
Erişim🔓 Açık Erişim
Özet
Antidiabetic, anti-Alzheimer, general toxicity, and antioxidant activities of Salvia syriaca were evaluated. Phytochemical composition of the essential oil and methanolic extract of the plant were identified using gas chromatography-mass spectrometry and reverse-phase high-performance liquid chromatography-diode array detector techniques, respectively. Essential oil of S. syriaca exhibited strong cytotoxicity, antioxidant, α-amylase, and α-glucosidase inhibitory activities. Gas chromatography-mass spectrometry analysis showed that spathulenol (87.4%), isospathulenol (7.6%), and bornyl acetate (2.7%) are the major compounds in essential oil. High-performance liquid chromatography analysis indicated that rutin, quercetin, apigenin, rosmarinic acid, and ferulic acid are the most abundant phenolic components. S. syriaca could be considered as a valuable source of bioactive natural compounds for functional foods, medical, and pharmaceutical applications.
Yazarlar (7)
1
Mir Babak Bahadori
2
Leila Dinparast
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Cengiz Sarikurkcu
5
Shahram Bahadori
6
Behvar Asghari
7
Nasrin Movahhedin
Anahtar Kelimeler
Alzheimer’s disease
Diabetes mellitus
Phenolic compounds
Rutin
Salvia syriaca
Spathulenol
Kurumlar
Biotechnology Research Center,Tabriz
Tabriz Iran
Imam Khomeini International University
Qazvin Iran
Research Center for Pharmaceutical Nanotechnology
Tabriz Iran
Selçuk Üniversitesi
Selçuklu Turkey
Süleyman Demirel Üniversitesi
Isparta Turkey
Urmia University of Medical Sciences
Urmia Iran
Metrikler
65
Atıf
7
Yazar
6
Anahtar Kelime