Scopus
🔓 Açık Erişim
Chemical characterization, antioxidant properties, anti-inflammatory activity, and enzyme inhibition of Ipomoea batatas L. leaf extracts
International Journal of Food Properties · Aralık 2017
Makale Bilgileri
DergiInternational Journal of Food Properties
Yayın TarihiAralık 2017
Cilt / Sayfa20 · 1907-1919
Scopus ID2-s2.0-85039159333
Erişim🔓 Açık Erişim
Özet
Ipomoea batatas L. is widely used as a functional food in many countries. In this work, I. batatas leaf extracts (Soxhlet extract, microwave [MW] extract, and decoction extract) were characterized for the first time, and their total flavonoid and phenolic compound contents were measured by spectrophotometric and chromatographic analyses. These extracts were investigated for their antioxidant activities (free radical scavenging and reducing power assays), enzyme inhibitory activities (cholinesterase, tyrosinase, α-amylase, and α-glucosidase) and effects on inflammation pathways. Various bioactive secondary metabolites were identified; among them, chlorogenic acid appeared to be the most abundant. The decoction extract displayed the highest level of phenolics (89.26 mg GAE/g extract) and thus exhibited stronger antioxidant ability than the Soxhlet and MW extracts. Each preparation was tested in in vitro enzymatic assays, which revealed that all three extracts exhibited interesting inhibitory activities against acetylcholinesterase, α-glucosidase, and α-amylase. Moreover, in vitro and ex vivo anti-inflammatory activities were observed for the decoction extract. Collectively, these results indicated that I. batatas leaf can be considered a potential candidate for the development of functional foods to combat the symptoms of metabolic disorders, such as type II diabetes mellitus.
Yazarlar (16)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Marcello Locatelli
ORCID: 0000-0002-0840-825X
3
Azzurra Stefanucci
4
Giorgia Macedonio
5
Ettore Novellino
6
Sako Mirzaie
7
Szabolcs Dvorácskó
8
Simone Carradori
9
Luigi Brunetti
10
Giustino Orlando
11
Luigi Menghini
ORCID: 0000-0002-7346-7395
12
Claudio Ferrante
13
Lucia Recinella
14
Annalisa Chiavaroli
ORCID: 0000-0002-3399-967X
15
Lidia Leporini
16
Adriano Mollica
Anahtar Kelimeler
Anti-inflammatory
Antioxidant
Enzyme inhibition
HPLC analysis
iNOS
Ipomoea batatas
Kurumlar
Islamic Azad University, Sanandaj Branch
Sanandaj Iran
Magyar Tudomanyos Akademia
Budapest Hungary
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Napoli Federico II
Naples Italy
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Metrikler
60
Atıf
16
Yazar
6
Anahtar Kelime