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Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits

Journal of Biomedical Materials Research - Part B Applied Biomaterials · Temmuz 2008

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YÖKSİS Kayıtları
Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits
Journal of Biomedical Materials Research Part B: Applied Biomaterials · 2008 SCI-Expanded
PROFESÖR ERCAN DURMUŞ →
Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits
Journal of Biomedical Materials Research Part B: Applied Biomaterials · 2008 SSCI
PROFESÖR İLHAMİ ÇELİK →

Makale Bilgileri

DergiJournal of Biomedical Materials Research - Part B Applied Biomaterials
Yayın TarihiTemmuz 2008
Cilt / Sayfa86 · 82-89
Erişim🔓 Açık Erişim
Özet The purpose of this study was to investigate the beneficial effects of particulate ostrich eggshell grafting on the healing of experimentally induced skull defects. The clinical, radiological, histological, and histomorphometrical findings of this material were compared with the results of commercially available demineralized bone matrix (DBM). The study was conducted on 18 adult New Zealand rabbits. One defect served as a control and the remaining ones either were filled with different sized eggshell particles or DBM, in each animal. Clinical and radiological inspections and histologic investigations of the animals were done at the 1st, 3rd, and 6th months of postoperative period. Radiologically, minimal bone regeneration was observed at the empty, control defect sites. The most advanced bone regeneration was in the DBM grafted defects. The eggshell particle grafted defect sites displayed weak bone regeneration at earlier stages, at 1st and 3rd months after operation when compared with demineralized bone matrix. Nevertheless, ossification was satisfactory at 6th month after operation when compared with the control defects. Within the limitations of this study, it was concluded that Ostrich eggshell powder (OSP) is a worth-while bone substitute because it is a safe, cheap, and easily available material. Long-term studies will clarify its possible role in maxillofacial surgery. Further sophisticated experiments should be undertaken before human implantation concerning its osteoproductive activity alone or in combination with other materials. © 2007 Wiley Periodicals, Inc.

Yazarlar (5)

1
Ercan Durmus
ORCID: 0000-0003-4851-4230
2
Ilhami Çelik
3
M. Faruk Aydin
4
Gülsün Yildirim
5
Emrah Sur

Anahtar Kelimeler

Bone graft material Eggshell powder Osteoproductive potential

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

35
Atıf
5
Yazar
3
Anahtar Kelime

Sistemimizdeki Yazarlar