Scopus
🔓 Açık Erişim
A comparative assessment of biological effects and chemical profile of Italian asphodeline lutea extracts
Molecules · Ocak 2018
Makale Bilgileri
DergiMolecules
Yayın TarihiOcak 2018
Cilt / Sayfa23
Scopus ID2-s2.0-85042228454
Erişim🔓 Açık Erişim
Özet
The present study aims to highlight the therapeutic potential of Asphodeline lutea (AL), a wild edible plant of the Mediterranean diet. Roots, aerial parts, and flowers of AL at two different phenological stages were collected from three locations in Italy. The inhibitory activities of extracts on strategic enzymes linked to human diseases were assessed. The antioxidant properties were evaluated in vitro, using six standard bioassays. The phenolic and anthraquinone profiles were also established using HPLC-PDA. Zinc, cadmium, lead, and copper contents were also determined. All the samples inhibited acetylcholinesterase (from 1.51 to 2.20 mg GALAEs/g extract), tyrosinase (from 7.50 to 25.3 mg KAEs/g extract), and α-amylase (from 0.37 to 0.51 mmol ACAEs/g extract). Aloe-emodin and physcion were present in all parts, while rhein was not detected. The phenolic profile and the heavy metals composition of specimens gathered from three different regions of Italy were different. It can be argued that samples collected near the street can contain higher concentrations of heavy metals. The experimental data confirm that the A. lutea species could be considered as a potential source of bioactive metabolites, and its consumption could play a positive and safe role in human health maintenance.
Yazarlar (12)
1
Dora Melucci
2
Marcello Locatelli
ORCID: 0000-0002-0840-825X
3
Clinio Locatelli
4
Alessandro Zappi
5
Francesco De Laurentiis
6
Simone Carradori
7
Cristina Campestre
8
Lidia Leporini
9
Gokhan Zengin
ORCID: 0000-0001-6548-7823
10
Carene Marie Nancy Picot-Allain
11
Luigi Menghini
ORCID: 0000-0002-7346-7395
12
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
Asphodeline lutea
Diabetes
Heavy metals
HPLC-PDA
Neurodegenerative disease
Tyrosinase
Kurumlar
Alma Mater Studiorum Università di Bologna
Bologna Italy
Interuniversity Consortium of Structural and Systems Biology
Roma Italy
Selçuk Üniversitesi
Selçuklu Turkey
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
University of Mauritius
Reduit Mauritius
Metrikler
22
Atıf
12
Yazar
6
Anahtar Kelime