Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, — an endemic medicinal plant from Turkey
Industrial Crops and Products · Mart 2018
YÖKSİS Kayıtları
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, - an endemic medicinal plant from Turkey
INDUSTRIAL CROPS AND PRODUCTS · 2018 SCI
Prof. Dr. GÖKHAN ZENGİN →
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, — an endemic medicinal plant from Turkey
INDUSTRIAL CROPS AND PRODUCTS · 2018 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, — an endemic medicinal plant from Turkey
INDUSTRIAL CROPS AND PRODUCTS · 2018 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer skin diseases and type II diabetes
2014 ISSN: 09266690 SCI-Expanded 4 atıf
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HPLC DAD analysis of phenolic compounds and antioxidant properties of Asphodeline lutea roots from Bulgaria and Turkey
2014 ISSN: 09266690 SCI-Expanded 1 atıf
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Phenolic constituent antioxidative and tyrosinase inhibitory activity of Ornithogalum narbonense L from Turkey A phytochemical study
2015 ISSN: 09266690 SCI-Expanded 1 atıf
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Composition antioxidant antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies subsp vulgare and subsp hirtum essential oils
2015 ISSN: 09266690 SCI-Expanded
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Changes in the fatty acid compositions and bioactivities of clary sage seeds depending on harvest year
2012 ISSN: 0926-6690 SCI-Expanded
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A phytochemical study on Potentilla anatolica An endemic Turkish plant
2015 ISSN: 09266690 SCI-Expanded
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Phenolic constituent antioxidative and tyrosinase inhibitory activity of Ornithogalum narbonense L from Turkey A phytochemical study
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Composition antioxidant antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies subsp vulgare and subsp hirtum essential oils
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
HPLC DAD analysis of phenolic compounds and antioxidant properties of Asphodeline lutea roots from Bulgaria and Turkey
2014 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer skin diseases and type II diabetes
2014 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Chemical and biological fingerprints of two Fabaceae species Cytisopsis dorycniifolia and Ebenus hirsuta Are they novel sources of natural agents for pharmaceutical and food formulations
2016 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
A study on in vitro enzyme inhibitory properties of Asphodeline anatolica New sources of natural inhibitors for public health problems
2016 ISSN: 09266690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response
2016 ISSN: 09266690 SCI
Prof. Dr. YÜKSEL KAN →
Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components
2018 ISSN: 09266690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
HPLC–MS/MS-based metabolic profiling and pharmacological properties of extracts and infusion obtained from Amelanchier parviflora var. dentata
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components
2018 ISSN: 0926-6690 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Lotus aegaeus (Gris.) Boiss and Iberis sempervirens L.: Chemical fingerprints, antioxidant potential, and inhibition activities and docking on key enzymes linked to global health problems
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Exploring the therapeutic potential and phenolic composition of two Turkish ethnomedicinal plants – Ajuga orientalis L. and Arnebia densiflora (Nordm.) Ledeb.
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, — an endemic medicinal plant from Turkey
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Makale Bilgileri
ISSN09266690
Yayın TarihiMart 2018
Cilt / Sayfa113 · 422-428
Scopus ID2-s2.0-85041379589
Özet
Ballota macrodonta Boiss. et Balansa., is a traditionally used endemic medicinal plant used to manage a plethora of diseases in Turkey. Nonetheless, few studies have endeavoured to highlight its therapeutic potential and its phytochemical profile. We hypothesized that B. macrodonta would possess multi-pharmacological propensities and bioactive compounds that would justify its use as a folk remedy. Aerial part of B. macrodonta was assessed for its antioxidant, antimicrobial, and enzymatic inhibitory potential using different extraction solvents. The total bioactive components determination and compound identification using High-Performance Liquid Chromatography with Diode-Array Detection (HPLC-DAD) method were used to correlate the biological properties. HPLC-DAD profile showed the presence of 19 components (e.g. hydroxybenzoic acid, catechin hydrate, vanillic acid, caffeic acid, syringic acid, epicatechin, coumaric acid, ferulic acid, luteolin-7-O-glucoside, rutin, and quercetin). The water and methanolic extracts showed high total phenolic and flavonoid contents, respectively. The overall antioxidant capacity of the water extract was higher than the one of the methanol extract. The extracts showed inhibitory activity against cholinesterases, tyrosinase, α-amylase and α-glucosidase. The extracts also presented antimicrobial activity against eight Gram positive/negative bacteria (MIC – 0.05–0.15 mg/mL) and eight fungi (MIC – 0.0125–0.20 mg/mL). The presence of active biomolecules with multi-pharmacological properties makes B. macrodonta a potential source of health-promoting compounds that can be exploited as a novel medicinal herbal product.
Yazarlar (12)
1
Sengul Uysal
2
Zaahira Aumeeruddy-Elalfi
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Abdurrahman Aktumsek
5
Andrei Mocan
6
Luisa Custodio
7
Nuno R. Neng
8
José M.F. Nogueira
9
Ana Ćirić
ORCID: 0000-0002-9478-5448
10
Jasmina Glamočlija
11
Marina Soković
ORCID: 0000-0002-7381-756X
12
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
Antimicrobial
Antioxidant
Ballotama crodonta
Enzyme inhibitor
Natural bioactive agents
Phenolics
Kurumlar
Faculdade de Ciências da Universidade de Lisboa
Lisbon Portugal
Selçuk Üniversitesi
Selçuklu Turkey
Universidade do Algarve
Faro Portugal
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
University of Belgrade
Belgrade Serbia
University of Mauritius
Reduit Mauritius
Scimago Dergi (ISSN Eşleşmesi)
Industrial Crops and Products
Q1
SJR Skoru0,974
H-Index186
YayıncıElsevier B.V.
ÜlkeNetherlands
Agronomy and Crop Science (Q1)
Metrikler
14
Atıf
12
Yazar
6
Anahtar Kelime