Scopus
Impact of different geographical locations on varying profile of bioactives and associated functionalities of caper (Capparis spinosa L.)
Food and Chemical Toxicology · Ağustos 2018
Makale Bilgileri
DergiFood and Chemical Toxicology
Yayın TarihiAğustos 2018
Cilt / Sayfa118 · 181-189
Scopus ID2-s2.0-85046779920
Özet
Capparis spinosa L. (caper), is a traditionally used medicinal plant and widely studied for its biological properties. We aimed for the first time to compare the biological and phenolic fingerprints of C. spinosa buds, collected from Morocco, Turkey, and Italy. Phenolic compounds, fatty acids, and essential oils were profiled by chromatographic techniques. Enzymes inhibitory activities of different extracts were tested by spectrophotometric methods. Antioxidant capacity was evaluated by different assays including free radical scavenging, reducing power, metal chelating and phosphomolybdenum. Moroccan sample showed the highest phenolic content across all extraction types followed by Italian and Turkish. Rutin was detected as main compounds in the extracts and the Italian decoction extract had highest rutin content. Moroccan samples exhibited the highest activity in microwave and Soxhlet extracts. The highest acetylcholinesterase inhibitory activity was observed in Turkish Soxhlet and Moroccan samples. The best butyrylcholinesterase inhibitory effects were also detected in the Italian extracts. The predominant fatty acid was α-linoleic acid (C 18:3 ω3; 28.65%), observed from Turkish sample. n-Hexadecanoic acid was the main component in the essential oils (13.9%, 25.03%, and 36.67% for Italian, Turkish, and Moroccan samples, respectively). Our results strongly advocate that future formulation of C. spinosa as active ingredient should also take into account the geographical origins and extraction techniques.
Yazarlar (8)
1
Azzurra Stefanucci
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Marcello Locatelli
ORCID: 0000-0002-0840-825X
4
Giorgia Macedonio
5
Chin Kun Wang
6
Ettore Novellino
7
Mohamad Fawzi Mahomoodally
8
Adriano Mollica
Anahtar Kelimeler
Antioxidant
Capparis spinosa
Enzyme inhibition
Essential oils
Fatty acids
Nutraceuticals
Kurumlar
Chung Shan Medical University
Taichung Taiwan
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Napoli Federico II
Naples Italy
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
University of Mauritius
Reduit Mauritius
Metrikler
54
Atıf
8
Yazar
6
Anahtar Kelime