Scopus
Sea rose (Armeria pungens (Link) Hoffmanns. & Link) as a potential source of innovative industrial products for anti-ageing applications
Industrial Crops and Products · Ekim 2018
Makale Bilgileri
DergiIndustrial Crops and Products
Yayın TarihiEkim 2018
Cilt / Sayfa121 · 250-257
Scopus ID2-s2.0-85047092035
Özet
This work explored for the first time the halophyte Armeria pungens (Link) Hoffmanns. & Link (sea rose) as a potential source of industrial natural products with anti-ageing potential. In this sense, ethyl acetate, acetone, ethanol and water extracts were prepared from flowers, peduncles and leaves of sea rose and evaluated for in vitro antioxidant capacity by four complementary methods and enzyme inhibitory effects towards enzymes related with the onset of different diseases, namely acetyl- (AChE) and butyrylcholinesterase (BuChE), α-glucosidase, tyrosinase, lipase and elastase. The polyphenolic composition of the extracts was appraised by high-pressure liquid chromatography coupled with diode array detection analysis (HPLC-DAD). Nineteen phenolic compounds were identified in the extracts, including flavonoids, hydroxybenzoic and hydroxycinnamic acids, and catechin was the main compound detected. The ethanol extract of sea rose leaves was the most effective as DPPH (IC50 = 83.7 μg/mL) and ABTS (IC50 = 146 μg/mL) scavenger, and also as a copper chelator (IC50 = 81.8 μg/mL). The acetone peduncles’ extract had the highest iron chelating activity (IC50 = 142 μg/mL). Water and ethanol leaf extracts showed the uppermost AChE inhibition (water: IC50 = 87.6 μg/mL; ethanol: IC50 = 90.3 μg/mL). In turn, the ethanol flower extract had the lowest IC50 values towards α-glucosidase (26.7 μg/mL) and tyrosinase (268 μg/mL). The leaf ethanol extract had the highest capacity to inhibit elastase (IC50 = 531 μg/mL), while none of the extracts had significant inhibitory activity on BuChE and lipase. In conclusion, ethanol extracts from leaves and flowers of sea rose showed to be the most promising source of natural products for industrial applications, with anti-ageing properties, namely neuroprotective, anti-diabetic, anti-wrinkles and anti-melanogenic activities.
Yazarlar (8)
1
Maria João Rodrigues
2
Catarina Pereira
ORCID: 0000-0002-1131-8773
3
Marta Oliveira
4
Nuno R. Neng
5
José M.F. Nogueira
6
Gokhan Zengin
ORCID: 0000-0001-6548-7823
7
Mohamad Fawzi Mahomoodally
8
Luisa Custodio
Anahtar Kelimeler
Acetylcholinesterase
Antioxidant
Elastase
Halophytes
Tyrosinase
α-Glucosidase
Kurumlar
Faculdade de Ciências da Universidade de Lisboa
Lisbon Portugal
Selçuk Üniversitesi
Selçuklu Turkey
Universidade do Algarve
Faro Portugal
University of Mauritius
Reduit Mauritius
Metrikler
17
Atıf
8
Yazar
6
Anahtar Kelime