Scopus
Phytol: A review of biomedical activities
Food and Chemical Toxicology · Kasım 2018
Makale Bilgileri
DergiFood and Chemical Toxicology
Yayın TarihiKasım 2018
Cilt / Sayfa121 · 82-94
Scopus ID2-s2.0-85052092268
Özet
Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil (EO) used as a fragrance and a potential candidate for a broad range of applications in the pharmaceutical and biotechnological industry. There is ample evidence that PA may play a crucial role in the development of pathophysiological states. Focusing on PYT and some of its most relevant derivatives, here we present a systematic review of reported biological activities, along with their underlying mechanism of action. Recent investigations with PYT demonstrated anxiolytic, metabolism-modulating, cytotoxic, antioxidant, autophagy- and apoptosis-inducing, antinociceptive, anti-inflammatory, immune-modulating, and antimicrobial effects. PPARs- and NF-κB-mediated activities are also discussed as mechanisms responsible for some of the bioactivities of PYT. The overall goal of this review is to discuss recent findings pertaining to PYT biological activities and its possible applications.
Yazarlar (34)
1
Muhammad Torequl Islam
2
Eunüs S. Ali
3
Shaikh J. Uddin
4
Subrata Shaw
5
Md Amirul Islam
6
Md Iqbal Ahmed
7
Manik Chandra Shill
8
Utpal Kumar Karmakar
9
Nagendra Sastry Yarla
10
Ishaq N. Khan
11
Md Morsaline Billah
12
Magdalena D. Pieczynska
13
Gokhan Zengin
ORCID: 0000-0001-6548-7823
14
Clemens Malainer
15
Ferdinando Nicoletti
16
Diana Gulei
17
Ioana Berindan-Neagoe
18
Apostol Apostolov
19
Maciej Banach
20
Andy Wai Kan Yeung
ORCID: 0000-0003-3672-357X
21
Amr El-Demerdash
22
Jianbo Xiao
23
Prasanta Dey
24
Santosh Yele
25
Artur Jóźwik
26
Nina Strzałkowska
27
Joanna Marchewka
28
Kannan RR Rengasamy
29
Jarosław Olav Horbańczuk
30
Mohammad Amjad Kamal
31
Mohammad S. Mubarak
ORCID: 0000-0002-9782-0835
32
Siddhartha K. Mishra
ORCID: 0000-0003-1627-1377
33
Jamil A. Shilpi
34
Atanas G. Atanasov
Anahtar Kelimeler
Biological activities
Phytanic acid
Phytol
Phytol metabolites
Plant-derived compounds
Kurumlar
Agricultural Institute - Shumen
Shumen Bulgaria
Broad Institute
Cambridge United States
Dr. H. S. Gour Vishwavidyalaya Sagar
Sagar India
Enzymoics
Sydney Australia
Faculty of Science
Mansoura Egypt
Independent Researcher
Vienna Austria
Institute of Chinese Medical Sciences
Taipa Macao
Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences
Magdalenka Poland
Institute of Oncology Cluj
Cluj Romania
Instytut Centrum Zdrowia Matki Polki
Lodz Poland
“Iuliu Hatieganu” University of Medicine and Pharmacy
Cluj‐Napoca Romania
Khulna University
Khulna Bangladesh
Khyber Medical University
Peshawar Pakistan
King Abdulaziz University
Jeddah Saudi Arabia
Medical University of Lodz
Lodz Poland
Museum National d'Histoire Naturelle
Paris France
Narsee Monjee Institute of Management Studies University, Shirpur
Shirpur India
North South University
Dhaka Bangladesh
Northwestern University Feinberg School of Medicine
Chicago United States
Novel Global Community Educational Foundation
Hebersham Australia
REEF Environmental Consultancy
Puducherry India
Selçuk Üniversitesi
Selçuklu Turkey
Sungkyunkwan University
Seoul South Korea
The College of Medicine and Public Health
Adelaide Australia
The University of Hong Kong
Hong Kong Hong Kong
The University of Jordan
Amman Jordan
Ton-Duc-Thang University
Ho Chi Minh City Viet Nam
Università degli Studi di Catania
Catania Italy
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
Universität Wien
Vienna Austria
University of Hyderabad
Hyderabad India
Uniwersytet Zielonogórski
Zielona Gora Poland
Metrikler
262
Atıf
34
Yazar
5
Anahtar Kelime