Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
South African Journal of Botany · Ocak 2019
YÖKSİS Kayıtları
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
South African Journal of Botany · 2019 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
SOUTH AFRICAN JOURNAL OF BOTANY · 2019 SCI
PROFESÖR GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
South African Journal of Botany · 2019 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiSouth African Journal of Botany
Yayın TarihiOcak 2019
Cilt / Sayfa120 · 119-123
Scopus ID2-s2.0-85041918082
Erişim🔓 Açık Erişim
Özet
Traditionally used botanical remedies have attracted much interest as pharmacological targets in the management and/or treatment of several diseases. Recently, they have been probed as tyrosinase inhibitors for the management of epidermal hyperpigmentation. This study aims to investigate into the antioxidant and tyrosinase inhibitory potential of methanol, ethyl acetate, and water extracts of three medicinal plants (Consolida orientalis (J. Gay) Schrödinger, Onosma isauricum Boiss. & Heldr. and Spartium junceum L.), from Turkey. Methanolic extract of O. isauricum and S. junceum showed the highest phenolic (63.08 mgGAE/g extract) and flavonoid contents (45.55 mgRE/g extract). Additionally, O. isauricum methanolic extract exhibited the most powerful antioxidant capacity followed by methanolic extract of S. junceum (86.02 and 62.81 mgAAE/g extract, respectively). S. junceum extracts yielded the higher kojic acid equivalent values (21.42–23.04 mgKAE/g extract), confirming that these extracts were the most potent inhibitors of tyrosinase. S. junceum showed promising activity that warrant further studies and could be considered as a potent candidate for the development of phytoremedies for the management of epidermal hyperpigmentation. To the best of our knowledge, this study can be considered as the first report of on the antioxidant and tyrosinase inhibitory action of C. orientalis, O. isauricum, and S. junceum from Turkey.
Yazarlar (6)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Mohamad Fawzi Mahomoodally
3
Carene Marie Nancy Picot-Allain
4
Yavuz Selim Cakmak
5
Sengul Uysal
6
Abdurrahman Aktumsek
Anahtar Kelimeler
Antioxidant
Botanical remedies
Enzyme inhibitors
Flavonoid
Hyperpigmentation
Phenolic
Tyrosinase
Kurumlar
Aksaray Üniversitesi
Aksaray Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Mauritius
Reduit Mauritius
Metrikler
22
Atıf
6
Yazar
7
Anahtar Kelime