Scopus
🔓 Açık Erişim
Antioxidant and enzyme inhibitory activities of disodium rabdosiin isolated from Alkanna sfikasiana Tan, Vold and Strid
South African Journal of Botany · Ocak 2019
Makale Bilgileri
DergiSouth African Journal of Botany
Yayın TarihiOcak 2019
Cilt / Sayfa120 · 157-162
Scopus ID2-s2.0-85046823912
Erişim🔓 Açık Erişim
Özet
Alkanna sfikasiana Tan, Vold and Strid is an endemic Greek species of Boraginaceae family. From the roots, the new natural product disodium rabdosiin (1) along with rosmarinic acid (2) were isolated from the methanolic extract and lanosta-7,24-dien-3β-ol (3) and linoleic acid (4) from the cyclohexane extract. From the methanolic extract of the aerial parts two flavonoids quercetin 3-Ο-β-D-glucoside (5) and quercetin 3-Ο-β-D-rutinoside (6) were isolated. The antioxidant properties exhibited good radical scavenging activity (96.00 mgTE/g for DPPH; 441.97 mgTE/g for ABTS) and reducing power ability (720.81 mgTE/g for CUPRAC and 413.94 mgTE/g for FRAP) for the new compound 1. Enzyme inhibitory activity has been also evaluated, showing inhibitory effects on AChE (4.32 mgGALAE/g), BChE (3.63 mgGALAE/g) and α-amylase (3.83 mmolACAE/g). Consequently, our study could provide a potential candidate for developing novel phyto-pharmaceutics and it could be considered a new starting point on the studied species.
Yazarlar (5)
1
T. Tufa
2
H. Damianakos
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Konstantia Graikou
ORCID: 0000-0001-6648-558X
5
Ioanna Chinou
Anahtar Kelimeler
Alkanna sfikasiana
Disodium rabdosiin
Enzymatic bioassays
Kurumlar
National & Kapodistrian University of Athens, School of Health Sciences
Athens Greece
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
15
Atıf
5
Yazar
3
Anahtar Kelime