Scopus
🔓 Açık Erişim
Biological activity of extracts of traditional wild medicinal plants from the Balkan Peninsula
South African Journal of Botany · Ocak 2019
Makale Bilgileri
DergiSouth African Journal of Botany
Yayın TarihiOcak 2019
Cilt / Sayfa120 · 213-218
Scopus ID2-s2.0-85049318181
Erişim🔓 Açık Erişim
Özet
The aim of the present study was to investigate antioxidant, cytotoxic and enzyme-inhibitory activities of wild growing medicinal herbs in the Balkan Peninsula (Morus nigra L., Symphytum officinale L., Sambucus nigra L., Teucrium chamaedrys L. and Teucrium montanum L.). Notably, antioxidant activity of investigated plant species was confirmed through several assays including free radical scavenging (ABTS), reducing power (CUPRAC), phosphomolybdenum and metal chelating test. Cytotoxic activity was evaluated using three different cell lines: Hep2c, RD and L2OB. S. officinale L. and S. nigra L. showed the highest cytotoxic activity. All studied extracts exhibited remarkable inhibitory effects on tested enzymes. S. nigra L. and T. chamaedrys L. exhibited the strongest tyrosinase inhibitory effects (26.62 ± 0.77 extract and 14.72 ± 0.41 mg KAEs/g, respectively), while S. officinale L. was the most potent in terms on α-glucosidase inhibition (11.47 ± 0.05 mmol ACAE/g extract). The obtained results indicate that the extracts of the tested wild grown plants could be used which can be explored as natural medicines for the promotion of health.
Yazarlar (6)
1
Milena Terzić
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Saša Đurović
4
Pavle Mašković
5
Aleksandra Cvetanović Kljakić
6
Marija Radojković
Anahtar Kelimeler
Antioxidant activity
Cytotoxic activity
Enzyme-inhibitory activity
Extracts
Natural agents
Kurumlar
Institute of General and Physical Chemistry Serbia
Belgrade Serbia
Selçuk Üniversitesi
Selçuklu Turkey
University of Kragujevac
Kragujevac Serbia
University of Novi Sad
Novi Sad Serbia
Metrikler
22
Atıf
6
Yazar
5
Anahtar Kelime