Scopus
🔓 Açık Erişim
Central nervous system and analgesic profiles of Lippia genus
Revista Brasileira de Farmacognosia · Ocak 2019
Makale Bilgileri
DergiRevista Brasileira de Farmacognosia
Yayın TarihiOcak 2019
Cilt / Sayfa29 · 125-135
Scopus ID2-s2.0-85059512070
Erişim🔓 Açık Erişim
Özet
Many people use medicinal plants to relieve disorders related to the central nervous system, such as depression, epilepsy, anxiety and pain, even though the effectiveness of most of them has not yet been proven through scientific studies. Plants of the Lippia genus, Verbenaceae, are widely used in ethnobotany as a food, for seasoning and in antiseptic remedies. They are also marketed and used for the treatment of different types of pain, including stomach ache, abdominal pain and headache, as well as being used as sedatives, anxiolytics and anticonvulsants. Despite their widespread use, there are no reviews on the central nervous system profile of plants of this genus. Therefore, the databases Medline-PubMed, Embase, Scopus and Web of Science were searched using the terms Lippia and biologic activity. Thirty-five papers were found. Eleven species of Lippia showed central nervous system activity, with leaves and the aerial parts of plants being the most commonly used, especially in aqueous and ethanol extracts or volatile oil. The species are composed mainly of terpenoids and phenylpropanoids, including polyketides, flavonoids and in less quantity some alkaloids. Although several species of Lippia present analgesic activity, most studies have not explored the mechanisms responsible for this effect, however, there is some evidence that volatile oils and constituents of the extracts may be responsible for the relief of some CNS disorders, but the effects on pain modulation seem to be the most exploited so far.
Yazarlar (9)
1
Pollyana S. Siqueira-Lima
2
Fabiolla R.S. Passos
3
Angélica M. Lucchese
4
Irwin R.A. Menezes
5
Henrique Douglas Melo Coutinho
6
Adley A.N. Lima
7
Gokhan Zengin
ORCID: 0000-0001-6548-7823
8
Jullyana S.S. Quintans
9
Lucindo J. Quintans-Júnior
Anahtar Kelimeler
CNS disorders
Inflammation
Medicinal plants
Pain
Verbenaceae
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Universidade Estadual de Feira de Santana
Feira de Santana Brazil
Universidade Federal do Rio Grande do Norte
Natal Brazil
Universidade Regional do Cariri
Crato Brazil
Université Fédérale de Sergipe
Sao Cristovao Brazil
Metrikler
16
Atıf
9
Yazar
5
Anahtar Kelime