Scopus
🔓 Açık Erişim
Medicinal plants and natural products used in cataract management
Frontiers in Pharmacology · Ocak 2019
Makale Bilgileri
DergiFrontiers in Pharmacology
Yayın TarihiOcak 2019
Cilt / Sayfa10
Scopus ID2-s2.0-85069512172
Erişim🔓 Açık Erişim
Özet
Cataract is the leading reason of blindness worldwide and is defined by the presence of any lens opacities or loss of transparency. The most common symptoms of cataract are impaired vision, decreased contrast sensitivity, color disturbance, and glare. Oxidative stress is among the main mechanisms involved in the development of age-related cataract. Surgery through phacoemulsification and intraocular lens implantation is the most effective method for cataract treatment, however, there are chances of serious complications and irreversible loss of vision associated with the surgery. Natural compounds consisting of antioxidant or anti-inflammatory secondary metabolites can serve as potential leads for anticataract agents. In this review, we tried to document medicinal plants and plant-based natural products used for cataract treatment worldwide, which are gathered from available ethnopharmacological/ethnobotanical data. We have extensively explored a number of recognized databases like Scifinder, PubMed, Science Direct, Google Scholar, and Scopus by using keywords and phrases such as “cataract”, “blindness”, “traditional medicine”, “ethnopharmacology”, “ethnobotany”, “herbs”, “medicinal plants”, or other relevant terms, and summarized the plants/phytoconstituents that are evaluated in different models of cataract and also tabulated 44 plants that are traditionally used in cataract in various folklore medical practices. Moreover, we also categorized the plants according to scientific studies carried out in different cataract models with their mechanisms of action.
Yazarlar (12)
1
Devesh Tewari
ORCID: 0000-0002-5125-3791
2
Ovidiu Samoila
3
Diana Gocan
4
Andrei Mocan
5
Cadmiel Moldovan
6
Hari Prasad Devkota
ORCID: 0000-0002-0509-1621
7
Atanas G. Atanasov
8
Gokhan Zengin
ORCID: 0000-0001-6548-7823
9
Javier Echeverría
10
Dan C. Vodnar
11
Bianca Szabo
12
Gianina Crişan
Anahtar Kelimeler
Aldose reductase
Antioxidant
Cataract
Lens opacity
MAPK
Medicinal plants
Natural products
Kurumlar
Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences
Magdalenka Poland
Kumamoto University
Kumamoto Japan
Lovely Professional University
Phagwara India
Selçuk Üniversitesi
Selçuklu Turkey
Universidad de Santiago de Chile
Santiago Chile
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
Universitatea de Stiinte Agricole si Medicina Veterinara din Cluj-Napoca
Cluj Napoca Romania
Universität Wien
Vienna Austria
Metrikler
43
Atıf
12
Yazar
7
Anahtar Kelime