Scopus
YÖKSİS DOI Eşleşti
SJR Q2
In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L
International Journal of Environmental Health Research · Mayıs 2019
YÖKSİS Kayıtları
In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH · 2019 SCI
Prof. Dr. GÖKHAN ZENGİN →
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In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L
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Makale Bilgileri
ISSN09603123
Yayın TarihiMayıs 2019
Cilt / Sayfa29 · 237-245
Scopus ID2-s2.0-85054914756
Özet
The genus Rubus (Rosaceae) has great potential for and a history of use as natural agents in several traditional folk remedies. Based on this concept, this study focused on the antioxidant activities and enzyme inhibitory effects of extracts and fractions from Rubus caesius. Different chemical assays were performed to detect antioxidant capacity, namely, free radical scavenging (ABTS and DPPH assays), reducing power (CUPRAC and FRAP), phosphomolybdenum and metal chelating. Enzyme inhibitory effects were tested towards cholinesterases (AChE and BChE), tyrosinase, α-amylase and α-glucosidase. In addition, total amounts of phenolics and flavonoids were detected by colorimetric assays. Among the samples, the ethyl acetate fraction exhibited the strongest antioxidant potential with its higher concentration of total phenolics. The highest AChE and α-amylase inhibitory activities were observed in the diethyl ether fraction, while the n-butanol fraction had the strongest anti-tyrosinase inhibitor ability. The present study demonstrated that R. caesius may be considered a source of biologically active compounds to develop novel functional products or drugs in the pharmaceutical field.
Yazarlar (4)
1
Daniel Miroslaw Grochowski
2
Sengul Uysal
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Michał Tomczyk
ORCID: 0000-0002-4063-1048
Anahtar Kelimeler
antioxidant activity
enzyme inhibitory activity
polyphenolic compounds
Rosaceae
Rubus caesius
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Uniwersytet Medyczny w Bialymstoku
Bialystok Poland
Scimago Dergi (ISSN Eşleşmesi)
International Journal of Environmental Health Research
Q2
SJR Skoru0,561
H-Index68
YayıncıTaylor and Francis Ltd.
ÜlkeUnited Kingdom
Medicine (miscellaneous) (Q2)
Pollution (Q2)
Public Health, Environmental and Occupational Health (Q2)
Health, Toxicology and Mutagenesis (Q3)
Metrikler
39
Atıf
4
Yazar
5
Anahtar Kelime