Scopus
YÖKSİS DOI Eşleşti
SJR Q1
New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
Food Research International · Eylül 2019
YÖKSİS Kayıtları
New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
Food Research International · 2019 SCI
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effects of high protease activity flours and commercial proteases on cookie quality
2005 ISSN: 09639969 SCI-Expanded
Prof. Dr. MERYEM KARA →
Estimation of in vitro neuroprotective properties and quantification of rutin and fatty acids in buckwheat (Fagopyrum esculentum Moench) cultivated in Turkey
2012 ISSN: 0963-9969 SCI-Expanded Q1
Dr. Öğr. Üyesi SADİYE AYŞE ÇELİK →
Pharmacological and polyphenolic profiles of Phyllanthus phillyreifolius var. commersonii Müll. Arg: An unexplored endemic species from Mauritius
2019 ISSN: 0963-9969 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
2019 ISSN: 0963-9969 SCI
Prof. Dr. GÖKHAN ZENGİN →
Metabolomics profiling and biological properties of root extracts from two Asphodelus species: A. albus and A. aestivus
2020 ISSN: 0963-9969 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical characterization, antioxidant, enzyme inhibitory and cytotoxic properties of two geophytes: Crocus pallasii and Cyclamen cilicium
2020 ISSN: 0963-9969 SCI-Expanded
Prof. Dr. EVREN YILDIZTUGAY →
Comprehensive bioactivity and chemical characterization of the endemic plant Scorzonera hieraciifolia Hayek extracts: A promising source of bioactive compounds
2020 ISSN: 0963-9969 SCI-Expanded
Prof. Dr. EVREN YILDIZTUGAY →
A comprehensive evaluation of the chemical profiles and biological properties of six geophytes from Turkey: Sources of bioactive compounds for novel nutraceuticals
2021 ISSN: 0963-9969 SCI-Expanded Q1
Prof. Dr. EVREN YILDIZTUGAY →
Metabolomics profiling and biological properties of root extracts from two Asphodelus species: A. albus and A. aestivus
2020 ISSN: 0963-9969 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
UHPLC-QTOF-MS based metabolomics and biological activities of different parts of Eriobotrya japonica
2021 ISSN: 0963-9969 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
A novel material for the microbiological, oxidative, and color stability of salmon and chicken meat samples: Nanofibers obtained from sesame oil
2023 ISSN: 0963-9969 SCI-Expanded Q1
Dr. Öğr. Üyesi NAZİK MEZİYET DİLEK →
A novel material for the microbiological, oxidative, and color stability of salmon and chicken meat samples: Nanofibers obtained from sesame oil
2023 ISSN: 0963-9969 SCI-Expanded Q1
Doç. Dr. ALİ SAMET BABAOĞLU →
Makale Bilgileri
ISSN09639969
Yayın TarihiEylül 2019
Cilt / Sayfa123 · 414-424
Scopus ID2-s2.0-85065659864
Özet
Bunium species have been reported to be used both as food and in traditional medicines. The scientific community has attempted to probe into the pharmacological and chemical profiles of this genus. Nonetheless, many species have not been investigated fully to date. In this study, we determined the phenolic components, antimicrobial, antioxidant, and enzyme inhibitory activities of aerial parts of four Bunium species (B. sayai, B. pinnatifolium, B. brachyactis and B. macrocarpum). Results showed that B. microcarpum and B. pinnatifolium were strong antioxidants as evidenced in the DPPH, ABTS, CUPRAC, and FRAP assays. B. brachyactis was the most effective metal chelator, and displayed high enzyme inhibition against cholinesterase, tyrosinase, amylase, glucosidase, and lipase. The four species showed varied antimicrobial activity against each microorganism. Overall, they showed high activity against P. mirabilis and E. coli (MIC and MBC <1 mg mL−1). B. brachyactis was more effective against Aspergillus versicolor compared to the standard drug ketoconazole. B. brachyactis was also more effective than both ketoconazole and bifonazole against Trichoderma viride. B. sayai was more effective than ketoconazole in inhibiting A. fumigatus. B. sayai was most non-toxic to HEK 293 (cellular viability = 117%) and HepG2 (cellular viability = 104%). The highest level of TPC was observed in B. pinnatifolium (35.94 mg GAE g−1) while B. microcarpum possessed the highest TFC (39.21 mg RE g−1). Seventy four compounds were detected in B. microcarpum, 70 in B. brachyactis, 66 in B. sayai, and 51 in B. pinnatifolium. Quinic acid, chlorogenic acid, pantothenic acid, esculin, isoquercitrin, rutin, apigenin, and scopoletin were present in all the four species. This study showed that the four Bunium species are good sources of biologically active compounds with pharmaceutical and nutraceutical potential.
Yazarlar (11)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Mehmet Yavuz Paksoy
3
Muhammad Zakariyyah Aumeeruddy
4
Jasmina Glamočlija
5
Marina Soković
ORCID: 0000-0002-7381-756X
6
Alina Diuzheva
ORCID: 0000-0003-2090-1634
7
József Jekő
8
Zoltán Cziáky
9
Maria João Rodrigues
10
Luisa Custodio
11
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
antioxidant
Bunium
cytotoxicity
enzyme inhibitors
phytoconstituents
Kurumlar
Pavol Jozef Šafárik University in Košice
Kosice Slovakia
Selçuk Üniversitesi
Selçuklu Turkey
Universidade do Algarve
Faro Portugal
University of Belgrade
Belgrade Serbia
University of Mauritius
Reduit Mauritius
University of Munzur
Turkey
University of Nyíregyháza
Nyíregyháza Hungary
Scimago Dergi (ISSN Eşleşmesi)
Food Research International
Q1
SJR Skoru1,666
H-Index253
YayıncıElsevier Ltd
ÜlkeUnited Kingdom
Food Science (Q1)
Metrikler
21
Atıf
11
Yazar
5
Anahtar Kelime