Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
South African Journal of Botany · Eylül 2019
YÖKSİS Kayıtları
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
South African Journal of Botany · 2019 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
South African Journal of Botany · 2019 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2018 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potentialand bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
2019 ISSN: 0254-6299 SCI
Prof. Dr. NURANİYE ERUYGUR →
Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. MEHMET MUSA ÖZCAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiEylül 2019
Cilt / Sayfa125 · 505-510
Scopus ID2-s2.0-85071399471
Erişim🔓 Açık Erişim
Özet
Gundelia species are among significant key medicinal plants extensively utilized in folk medicine of Middle Eastern countries. This study focused on researching the biopharmaceutical potency and bioactive compounds of Gundelia rosea seed. Hereby, traditional knowledge-based preparing methods (infusion and decoction) and ethanol-based lyophilized extracts obtained from Gundelia rosea seeds were assessed for (i) antioxidant capacities, (ii) enzyme inhibitory activities, (iii) HPLC-MS/MS and (iv) GC–MS studies. Phytochemical analysis revealed that ethanol extract which primarily compromised of mainly phenolics (4-Caffeoylquinic acid and luteolin hexoside) and several fatty acids (palmitic, stearic, oleic and linoleic acids), was superior to those of infusion and decoction extracts. Antioxidant activities findings revealed that ethanol extract contained a high level of total phenolics (55.3 mg Gallic acid Eq./g extract) and had high capacities of reducing (1683 μmol Fe2+ and 214.1 mg Trolox Eq./g extract for FRAP and CUPRAC respectively) and radical scavenging (ORAC: 2241.9 μmol, DPPH: 91.7 mg, ABTS: 141.2 mg Trolox Eq./g extract) and total antioxidant (Phosphomolybdenum: 1.39 mmol Trolox Eq./g extract) properties. The suppressive abilities of the extracts against selected isolated enzymes revealed that ethanol extract had pronounced levels of inhibitory activities against AChE (4.3 mg Galanthamine Eq.), BChE (3.4 mg Galanthamine Eq.), tyrosinase (120 mg Kojic acid Eq.), amylase (0.61 mmol Acarbose Eq.), glucosidase (11.91 mmol Acarbose Eq.) and lipase (53.4 μmol Orlistat Eq.) per gram extract. Findings obtained within this study confirmed the traditional utilization of Gundelia rosea and suggest its potential as a novel candidate of biopharmaceutical agents for public health problems.
Yazarlar (5)
1
Abdullah Dalar
ORCID: 0000-0002-0080-2519
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Muzaffer Mukemre
4
A. S. Bengu
5
S. İşler
Anahtar Kelimeler
4-Caffeoylquinic acid
Biopharmaceuticals
Fatty acids
Gundelia rosea
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
University of Bingol
Bingol Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
10
Atıf
5
Yazar
4
Anahtar Kelime