Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Biopharmaceutical potential, chemical profile and in silico study of the seagrass – Syringodium isoetifolium (Asch.) Dandy
South African Journal of Botany · Aralık 2019
YÖKSİS Kayıtları
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
South African Journal of Botany · 2019 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2018 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potentialand bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
2019 ISSN: 0254-6299 SCI
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Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. MEHMET MUSA ÖZCAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiAralık 2019
Cilt / Sayfa127 · 167-175
Scopus ID2-s2.0-85073242647
Erişim🔓 Açık Erişim
Özet
Syringodium isoetifolium (Asch.) Dandy (Family: Cymodoceaceae) is a seagrass growing in the oceans across the globe except in cold waters. This study investigated into the polyphenolic content, antioxidant [2,2-diphenyl-1-picrylhydrazyl(DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), cupric reducing antioxidant capacity (CUPRAC), ferric reducing antioxidant power (FRAP), metal chelating, phosphomolybdenum)]and enzymatic properties [α-amylase, α-glucosidase, tyrosinase, acetylcholinesterase (AChE), butylcholinesterase (BChE)] of S. isoetifolium. Detailed phytochemical profiling was also conducted using Ultra Performance High-Pressure Liquid Chromatography (UHPLC) technique. The methanolic extract was found to possess greater amount of phenolic than flavonoid compounds. Antioxidant results showed that the extract was a better ABTS radical scavenger (9.56 ± 0.40 mg TE/g) compared to DPPH (5.39 ± 0.09 mg TE/g and exhibited good reducing potential with CUPRAC assay (18.66 ± 0.46 mg TE/g). In terms of enzymatic inhibition, strong activities were noted against tyrosinase (25.92 ± 0.11 mg KAE/g) in contrast to α-amylase, α-glucosidase and cholinesterase. Phytochemical data revealed the presence of 14 compounds with chicoric acid and caftaric acid among them. Docking the identified compounds, namely, caftaric acid, loliolide and Iso-loliolide at the active site of the tyrosinase enzyme has elucidated the binding affinity of these inhibitors and their interactions with the active site. Based on our findings, S. isoetifolium may be considered as a good natural antioxidant and clinical enzyme inhibitors that can be exploited in pharmaceutical/or cosmeceutical industries.
Yazarlar (9)
1
Kannan RR Rengasamy
2
Nabeelah Bibi Sadeer
ORCID: 0000-0002-0602-0059
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Mohamad Fawzi Mahomoodally
5
Zoltán Cziáky
6
József Jekő
7
Alina Diuzheva
ORCID: 0000-0003-2090-1634
8
Hassan H. Abdallah
9
Doo Hwan Kim
Anahtar Kelimeler
Antioxidant
Docking
Enzyme inhibitors
Phenolic
Phytoconstituents
S. isoetifolium
Kurumlar
Czech University of Life Sciences Prague
Prague Czech Republic
Konkuk University
Seoul South Korea
Salahaddin University-Erbil
Erbil Iraq
Selçuk Üniversitesi
Selçuklu Turkey
University of Mauritius
Reduit Mauritius
University of Nyíregyháza
Nyíregyháza Hungary
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
18
Atıf
9
Yazar
6
Anahtar Kelime