Scopus
🔓 Açık Erişim
Marine algae: A potential resource of Anti-HSV molecules
Processes · Aralık 2019
Makale Bilgileri
DergiProcesses
Yayın TarihiAralık 2019
Cilt / Sayfa7
Scopus ID2-s2.0-85079689404
Erişim🔓 Açık Erişim
Özet
Herpes simplex viruses (HSVs) are common human pathogens belonging to the subfamily alpha-herpesvirinae that trigger severe infections in neonates and immunocompromised patients. After primary infection, the HSVs establish a lifelong latent infection in the vegetative neural ganglia of their hosts. HSV infections contribute to substantial disease burden in humans as well as in newborns. Despite a fair number of drugs being available for the treatment of HSV infections, new, effective, and safe antiviral agents, exerting different mechanisms of action, are urgently required, mainly due to the increasing number of resistant strains. Accumulating pieces of evidence have suggested that structurally diverse compounds from marine algae possess promising anti-HSV potentials. Several studies have documented a variety of algal polysaccharides possessing anti-HSV activity, including carrageenan and fucan. This review aimed to compile previous anti-HSV studies on marine algae-derived compounds, especially sulfated polysaccharides, along with their mode of action, toward their development as novel natural anti-HSV agents for future investigations.
Yazarlar (8)
1
Mohamad Fawzi Mahomoodally
2
Devina Lobine
3
Kannan RR Rengasamy
4
Shanmugaraj Gowrishankar
ORCID: 0000-0001-5728-6837
5
Devesh Tewari
ORCID: 0000-0002-5125-3791
6
Gokhan Zengin
ORCID: 0000-0001-6548-7823
7
Doo Hwan Kim
8
Iyyakkannu Sivanesan
ORCID: 0000-0001-7447-6392
Anahtar Kelimeler
Antiviral
Brown algae
Green algae
Herpesviridae
Human infections
Natural product
Phytochemicals
Red algae
Sulfated polysaccharides
Virus
Kurumlar
Alagappa University
Karaikudi India
Konkuk University
Seoul South Korea
Lovely Professional University
Phagwara India
Selçuk Üniversitesi
Selçuklu Turkey
University of Mauritius
Reduit Mauritius
Metrikler
14
Atıf
8
Yazar
10
Anahtar Kelime